Novo Nordisk (NVO) is a global healthcare company and a prominent player in the diabetes market with a full portfolio of glucagon-like peptide 1 (GLP-1) receptor agonists, modern insulins and human insulins. Based in Bagsværd, Denmark the company is also a key player in hemophilia care, growth hormone therapy, hormone replacement therapy and obesity.
Wegovy, Novo Nordisk’s blockbuster obesity product, was approved by the FDA in June 2021. Since then, the drug has undergone several label expansions and helped explode Novo sales by more than double in four years, from under $23 billion to nearly 48 billion.
Profits also surged 125% during the same period, from $1.65 to $3.82 on a 12-month trailing basis.
The reason this terrific growth story is a Zacks #5 Rank is that Wall Street analysts have dropped their estimates for the earnings outlook with 2025 full-year consensus falling from $3.84 to $3.57 in the past 90 days.
2026 full-year EPS concurrently fell from $3.95 to $3.51, representing a 1.8% annual decline.
All this despite a big 32% earnings beat on Nov 5 and FDA approval for oral Wegovy, the first GLP-1 obesity pill in the U.S. You can learn more about that development in this article, which also addressed competitive threats from smaller biotech players...
NVO's First Oral Obesity Pill Approval: What Does it Mean for Lilly?
Another stock experiencing high volatility due to the diet-drug wars is Hims & Hers (HIMS). They are not a drug-maker but a consumer delivery platform that seems to have on-again, off-again access to the competing drugs because of regulatory influence from the giant pharma companies.
HIMS shares have plummeted 45% from a close above $60 in October to $34. You can learn more about their recent cross-roads here...
Hims & Hers Expands Subscription-Led Care as Platform Engagement Grows
In conclusion, even the Wall Street spreadsheet jockeys don't have a firm handle on this evolving market with 8 covering analysts dispersing their price targets for NVO to an average of $52 (where the stock is now), and a high/low of $70/$42.
Maybe the best move right now for investors is to be like Tim "Apple" and buy something on sale that also helps with obesity: Nike, the weight-loss shoe.
Zacks Naming Top 10 Stocks for 2026
Want to be tipped off early to our 10 top picks for the entirety of 2026? History suggests their performance could be sensational.
From 2012 (when our Director of Research Sheraz Mian assumed responsibility for the portfolio) through November, 2025, the Zacks Top 10 Stocks gained +2,530.8%, more than QUADRUPLING the S&P 500’s +570.3%.
Now Sheraz is combing through 4,400 companies to handpick the best 10 tickers to buy and hold in 2026. Don’t miss your chance to get in on these stocks when they’re released on January 5.
Be First to New Top 10 Stocks >>Novo Nordisk A/S (NVO) : Free Stock Analysis Report
Hims & Hers Health, Inc. (HIMS) : Free Stock Analysis Report
This article originally published on Zacks Investment Research (zacks.com).
The views and opinions expressed herein are the views and opinions of the author and do not necessarily reflect those of Nasdaq, Inc.