DNA helix abstract graphic

    Nasdaq Biotech Index

    Pioneer the Possible

    With disruption in our DNA, we are home to today’s top and emerging biotech companies, helping them pioneer a better tomorrow.

    The Benchmark for Technology-Driven Healthcare Innovation


    BioTechnology Index

    With its rules-based, transparent index methodology utilizing modified market cap-weighting, the Nasdaq Biotechnology Index (NBI) reflects the dynamic, innovation-driven world of Nasdaq-listed biotech companies. NBI captures hundreds of constituents of various sizes, while ensuring that the largest, most important players in the space are weighted appropriately.

    Learn more    Read the Year in Review Report

    Index Charts & Data

    Top 10 Index Weights as of December 31, 2021

    Top 10 Index Weights as of December 31, 2021 (%)

    Top 10 Index Weights

    Top 10 Index Weights: FY'21 vs. FY'20 Returns (%)

    Investing in Biotech with Nasdaq Index

    Invesco Nasdaq Biotechnology ETF

    Biotech is paving the way for a post-pandemic world. Through the Invesco Nasdaq Biotechnology ETF, access a high concentration of companies critical to COVID-19 vaccines and treatments, as well as the continued growth of genomics, wellness and advanced medical therapeutics.

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    ETPs Tracking NBI

    Given the strength of the Nasdaq Biotech Index, numerous exchange-traded products are tracking the index. From Asia to North America and Europe to the Middle East, discover the global reach of NBI.

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    Invesco Logo

    "We are excited to expand our relationship with Nasdaq in order to offer investors another way to access innovative companies currently shaping the way we live and work."

    Nasdaq Biotech Index on TradeTalks

    Trends In Biotech Listings And IPO Pipeline
    Nasdaq Head of Healthcare Listings, & Capital Markets Jordan Saxe joins Jill Malandrino on TradeTalks to discuss trends in biotech listings and IPO pipeline. #NationalBiotechnologyMonth
    Jan 31, 2022
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    Pillars of Possibilities

    Home to 600+ Biotech Companies



    Backing BioTech Since the Beginning

    We've backed biotech for 50 years and counting, providing the disruptors and innovators with a place to call home and access to the capital they need to propel their businesses forward. 98% of U.S. Listed Biotech Companies are listed on Nasdaq. 

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    Accelerate Innovation

    Unlocking Opportunity

    We connect today's biotech trailblazers and titans with the capital they need to unlock opportunity and accelerate innovation that transforms lives.

    Quarter of a Century

    Benchmarking Innovation

    The Nasdaq Biotech Index has provided a benchmark for biotech innovation for more than 25 years.

    Global Impact

    Investing in Tomorrow

    Learn how to invest in the Nasdaq Biotech Index and help accelerate the global impact of the companies who are changing the world.

    Portrait photography of Jordan Saxe in front of a Nasdaq promotional screen.

    "We are the home to Biotech because we committed to the industry from the very beginning. Our gateway to the capital markets allows researchers, scientists and business leaders to pioneer the possible every day—and we are proud to be with them at every step of that journey."

    NBI in the News

    cell being injected with needle

    Nasdaq: MRNA

    Moderna Announces FDA Authorization of Its COVID-19 Vaccine in U.S.

    In December 2020, Moderna COVID-19 Vaccine was authorized for distribution and use under an Emergency Use Authorization (EUA). Delivery to the U.S. Government began immediately.

    biotech 2

    Nasdaq: AMGN

    Amgen Wins Approval for Pathbreaking Lung Cancer Drugs

    A potential blockbuster, this new drug is first to treat common cancer mutation called KRAS that researchers struggled for years to target.


    Nasdaq: BNTX

    BioNTech to roll out mRNA Production in Africa

    Pharmaceutical company BioNTech has announced plans to establish mRNA vaccine production facilities in Africa — part of a larger plan to combat diseases on the continent.

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    What's Next For the Innovators of the Nasdaq Biotechnology Index?

    Biotech's Post-Covid Future

    Learn what drove biotech performance in the pivotal year of 2021, and why having the proper benchmark for this unique industry is more important than ever. Along with a special guest from Nasdaq-listed BioMarin Pharmaceutical, take a deep dive into some of the cutting-edge innovation happening within the space, especially as it relates to gene therapy for the treatment of rare diseases.

    Register now ->