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ORBIMED ADVISORS LLC Information

601 LEXINGTON AVENUE, NEW YORK, New York, 10022, (212) 739-6400

Report Date: 03/31/2019

Position Statistics

Total Positions 141
New Positions 18
Increased Positions 43
Decreased Positions 52
Positions with Activity 95
Sold Out Positions 26
Total Mkt Value (in $ millions) 5,907

Institutional Holdings information is filed by major institutions on form 13-F with the Securities and Exchange Commission.

Sector Weighting

Energy
Basic Materials
Industrials
Consumer Cyclicals
Consumer Non-Cyclicals
Financials 1.57%
Healthcare 97.84%
Technology 0%
Telecommunication Services
Utilities

141 Positions as of 03/31/2019

Company Class Value of Shares ($1,000s) ▼ Change in Value ($1,000s) Change (%) Shares Held
ASCENDIS PHARMA A S SPONSORED ADR 479,062 -14,080 (2.86) 3,970,673
TRICIDA INC COM 382,758 New 10,889,280
ALEXION PHARMACEUTICALS INC COM 244,944 -11,289 (4.41) 1,957,200
BOSTON SCIENTIFIC CORP COM 241,575 New 5,790,400
ALECTOR INC COM 234,909 234,909 New 13,182,329
MERCK & CO INC COM 219,075 6,402 3.01 2,570,100
VERTEX PHARMACEUTICALS INC COM 172,097 -32,049 (15.7) 955,300
NEUROCRINE BIOSCIENCES INC COM 148,178 108,231 270.94 1,833,200
EDWARDS LIFESCIENCES CORP COM 137,251 47,875 53.57 715,000
GUARDANT HEALTH INC COM 132,931 New 1,534,464
THERMO FISHER SCIENTIFIC INC COM 131,296 2,877 2.24 447,300
WRIGHT MED GROUP N V ORD SHS 123,331 -21,148 (14.64) 4,187,799
IOVANCE BIOTHERAPEUTICS INC COM 120,676 New 5,548,326
INTUITIVE SURGICAL INC COM NEW 109,467 20,717 23.34 210,300
SAREPTA THERAPEUTICS INC COM 102,854 5,885 6.07 828,400
EHEALTH INC COM 92,784 6,379 7.38 1,181,214
ANTHEM INC COM 92,741 5,647 6.48 325,200
BAUSCH HEALTH COS INC COM 91,198 3,423 3.90 3,740,700
MYLAN N V SHS EURO 90,673 16,330 21.97 4,861,800
PRINCIPIA BIOPHARMA INC COM 88,985 New 2,605,713