Theravance Biopharma (TBPH) Q2 Loss Narrows, Shares Up

Shutterstock photo

Theravance Biopharma, Inc. TBPH reported second-quarter 2018 loss of $0.76 per share, narrower than the Zacks Consensus Estimate of a loss of $1.24 and the year-ago loss of $1.27.

Total revenues in the quarter under review surged a massive 475% year over year to $23 million owing to higher revenues from Theravance's only marketed drug Vibativ as well as higher collaboration revenues. Moreover, the top line surpassed the Zacks Consensus Estimate of $10.5 million.

Shares of Theravance were up 7.1% on Aug 1 following the company's earnings release. However, the stock has decreased 8.1% so far this year, wider than the industry's decline of 1.2%.

Quarterly Details

Vibativ generated U.S. revenues of $5.4 million in the second quarter, up 53% from the year-ago period's figure. Revenues from collaborations were $18.11 million compared with $35,000 in the year-earlier quarter. This upside can mainly be attributed to revenues recognized with respect to the opt-in payment received from Alfasigma for velusetrag and upfront payment from J&J JNJ for the commercialization agreement of TD-1473 to treat inflammatory diseases.

Research and development expenses were $48.6 million, up 13.3% from the year-ago period while selling, general & administrative expenses rose 2.9% to $25 million.

Pipeline and Other Updates

In February 2018, Theravance entered into a global collaboration agreement with Janssen to jointly develop and commercialize its pan-Janus kinase inhibitor, TD-1473, for the treatment of inflammatory intestinal diseases. A phase II and a phase IIb/III study are likely to be initiated in third and fourth-quarter 2018 to evaluate TD-1473 in Crohn's disease and ulcerative colitis, respectively.

In January, Theravance along with partner Mylan MYL announced that the new drug application (NDA) for its pipeline candidate, Yupelri (revefenacin) (TD-4208), has been accepted by the FDA for treatment of adults with chronic obstructive pulmonary disease (COPD). A response from the regulatory body is expected on Nov 13, 2018. The company is preparing for the commercial launch of the drug upon potential approval.

An approval will be a huge boost considering that Yupelri will be the first once daily nebulized long-acting muscarinic antagonist (LAMA) option for COPD patients.

In April, Theravance Biopharma highlighted that the FDA has approved a label expansion of Glaxo's GSK once-daily, single inhaler triple combination therapy, Trelegy Elipta, to include COPD patients with airflow limitation or those who have experienced an acute worsening of respiratory symptoms. Theravance has 85% economic interest in royalties paid by Glaxo on Trelegy Elipta's global sales.

In the second quarter of 2018, Glaxo recorded Trelegy Elipta's sales of $36.5 million. While Theravance is eligible to receive 5.5-8.5% (tiered) of the product's worldwide net sales.

A regulatory application has also been submitted by Glaxo to the Japanese Ministry of Health, Labour and Welfare, seeking an approval for Trelegy Ellipta pertaining to the treatment of COPD.

2018 Outlook Reiterated

Theravance continues to expect operating loss excluding non-cash share-based compensation for 2018 in the range of $180-$200 million.

Theravance Biopharma, Inc. Price, Consensus and EPS Surprise

Theravance Biopharma, Inc. Price, Consensus and EPS Surprise | Theravance Biopharma, Inc. Quote

Zacks Rank & Key Picks

Theravance Biopharma carries a Zacks Rank #3 (Hold). You can see the complete list of today's Zacks #1 Rank (Strong Buy) stocks here .

Today's Stocks from Zacks' Hottest Strategies

It's hard to believe, even for us at Zacks. But while the market gained +21.9% in 2017, our top stock-picking screens have returned +115.0%, +109.3%, +104.9%, +98.6%, and +67.1%.

And this outperformance has not just been a recent phenomenon. Over the years it has been remarkably consistent. From 2000 - 2017, the composite yearly average gain for these strategies has beaten the market more than 19X over. Maybe even more remarkable is the fact that we're willing to share their latest stocks with you without cost or obligation.

See Them Free>>

Want the latest recommendations from Zacks Investment Research? Today, you can download 7 Best Stocks for the Next 30 Days. Click to get this free report

Johnson & Johnson (JNJ): Free Stock Analysis Report

GlaxoSmithKline plc (GSK): Free Stock Analysis Report

Theravance Biopharma, Inc. (TBPH): Free Stock Analysis Report

Mylan N.V. (MYL): Free Stock Analysis Report

To read this article on click here.

Zacks Investment Research

The views and opinions expressed herein are the views and opinions of the author and do not necessarily reflect those of Nasdaq, Inc.

The views and opinions expressed herein are the views and opinions of the author and do not necessarily reflect those of Nasdaq, Inc.

In This Story


Other Topics


Latest Markets Videos


    Zacks is the leading investment research firm focusing on stock research, analysis and recommendations. In 1978, our founder discovered the power of earnings estimate revisions to enable profitable investment decisions. Today, that discovery is still the heart of the Zacks Rank. A wealth of resources for individual investors is available at

    Learn More