World Markets
PFE

Pfizer Discontinues Phase 2b STRIVE Clinical Trial Due To Futility

Using a smartphone to calculate data

(RTTNews.com) - Pfizer Inc. ( PFE ) announced Thursday that independent Data Monitoring Committee or DMC recommended discontinuation of the Phase 2b STRIVE Clinical Trial of Staphylococcus aureus Vaccine following planned interim analysis.

The company said the Phase 2b trial STRIVE (STaphylococcus aureus SuRgical Inpatient Vaccine Efficacy) evaluating the company's investigational Staphylococcus aureus or S. aureus multi-antigen vaccine or PF-06290510 is being discontinued due to futility.

The DMC concluded from these data that the study reached futility, meaning that there is low statistical probability for the study to meet the pre-defined primary efficacy objective in adults undergoing elective spinal fusion surgery after completing a planned Phase 3 expansion of the study.

A safety review by the DMC indicated that the investigational vaccine has been safe and well tolerated. STRIVE trial participants who are enrolled in the study will complete the study's follow-up evaluations.

Pfizer is evaluating next steps for the potential development of a S. aureus vaccine.

Read the original article on RTTNews (http://www.rttnews.com/2964785/pfizer-discontinues-phase-2b-strive-clinical-trial-due-to-futility.aspx)

For comments and feedback: contact editorial@rttnews.com


The views and opinions expressed herein are the views and opinions of the author and do not necessarily reflect those of Nasdaq, Inc.

In This Story

PFE

Other Topics

Stocks Technology

RTTNews

Founded in the late 1990s by Andrew Mariathasan in New York, with the goal of covering Wall Street for a new generation of investors, RTTNews has expanded steadily over the years to become a trusted provider of content for a wide array of subjects across several platforms. RTT's Financial Newswire is relied upon by some of the world's largest financial institutions, including banks, brokerages, trading platforms and financial exchanges.

Learn More