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Minerva Presents Additional Data from Schizophrenia Drug

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Minerva Neurosciences, Inc.NERV announced the results of additional data analyses from phase IIb study of MIN-101, as monotherapy in patients with negative symptoms of schizophrenia.

Minerva's share price has gained 98.5% in the past one year, while the Zacks classified Medical-Drugs industry witnessed a fall of 13.1%.

Coming back to the latest release, the additional data showed significant improvements in several sub-tests of cognitive functioning, including motor tests and verbal fluency in patients with schizophrenia. Deficits in these capabilities are associated with poor interpersonal and real-world functioning for these patients.

Cognitive impairment is a core feature of schizophrenia, which affects up to 75% of the patients population. Earlier in May 2016, the company announced top-line results from 12-week core phase of the study that showed that the study met its primary endpoint - the patients experienced statistically significant improvement of negative symptoms when treated with MIN-101 as compared to placebo. Statistically significant benefit of MIN-101 was also demonstrated in multiple secondary endpoints.

Further in Oct 2016, Minerva announced data from the 24-week open-label extension of its 12-week, phase IIb study of MIN-101. Data from the extension phase demonstrated a further and continuous improvement in negative symptoms in patients with schizophrenia.

Minerva's other pipeline candidates, include MIN-117 which is in clinical development for major depressive disorder (MDD), MIN-202 which is in clinical development for insomnia and MDD; and MIN-301 which is in pre-clinical development for Parkinson's disease.

Zacks Rank & Key Picks

Minerva currently carries a Zacks Rank #3 (Hold). Some better-ranked stocks in the health care sector include Enzo Biochem, Inc. ENZ , Sunesis Pharmaceuticals, Inc. SNSS and Anika Therapeutics Inc. ANIK . While Enzo Biochem sports a Zacks Rank #1 (Strong Buy), Sunesis and Anika carry a Zacks Rank #2 (Buy). You can see the complete list of today's Zacks #1 Rank stocks here .

Enzo Biochem's loss estimates for 2017 narrowed 5.88% over the past 60 days. The company recorded a positive earnings surprise in three of the last four quarters, the average being 22.50%. Its share price was up 44.9% in the past one year.

Sunesis' loss estimates narrowed 5.06% and 8.80% for 2017 and 2018, respectively, over the past 60 days. The company recorded a positive earnings surprise in three of the last four quarters, the average being 0.54%.

Anika's earnings estimates for 2016 and 2017 were up 3.9% and 0.5%, respectively, over the last 60 days. The company recorded a positive earnings surprise in each of the last four quarters, the average being 37.8%. Its share price was up 36% in the past one year.

Minerva Neurosciences Inc. Price

Minerva Neurosciences Inc. Price | Minerva Neurosciences Inc. Quote

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The views and opinions expressed herein are the views and opinions of the author and do not necessarily reflect those of Nasdaq, Inc.


The views and opinions expressed herein are the views and opinions of the author and do not necessarily reflect those of Nasdaq, Inc.

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