Top Health-care stocks:
Health care shares were mostly unchanged in pre-market trade Tuesday.
In health care stocks news, Karyopharm Therapeutics ( KPTI ) was up 17.2% after it said its drug Selinexor achieved positive phase 2b results in treating multiple myeloma, a type of bone-blood cancer. The company said it plans to start a phase 3 study in early 2017 to evaluate Selinexor in combination with the drugs bortezomib and dexamethasone. Based on test results, Karyopharm said it may apply for a Food and Drug Administration grant of accelerated approval of Selinexor, but also said approval is not assured.
And, Tonix Pharmaceuticals Holding ( TNXP ) fell 32.1%, eyeing a new three-year low, after the drug developer reported preliminary topline results from its phase 3 Affirm clinical study evaluating the safety and efficacy of TNX-102 SL in patients with fibromyalgia. The study did not achieve statistical significance in the primary efficacy endpoint: the proportion of patients who reported a 30% or greater reduction in pain from baseline to the end of the 12-week treatment period. However, the drug showed statistically significant effects on pain when analyzed by other standard statistical approaches.
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