Top Health-care stocks:
Health-care shares were mainly unchanged in pre-market trade on Wednesday.
In health-care stocks news, Integra LifeSciences Holdings ( IART ) said pre-market Wednesday it made a binding offer to acquire Johnson & Johnson's ( JNJ ) Codman Neurosurgery business for $1.05 billion in cash.
Shares in the company were unchanged at $43.25 pre-bell. The stock has traded between $27.96 and $45.50 over the past 52 weeks.
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