GSK

GlaxoSmithKline's chronic disease treatment study meets late-stage main goals

Credit: REUTERS/PETER NICHOLLS

Adds detaiks on study

April 3 (Reuters) - GlaxoSmithKline plc GSK.L said on Friday its treatment for a chronic inflammatory disease of the nasal passage linings or sinuses met the main goals in a late-stage study.

The treatment, Nucala, was tested in patients with a form of chronic rhinosinusitis who had a history of previous surgery and needed further surgery due to severe symptoms or worsening of the condition, the British drugmaker said.

Chronic rhinosinusitis causes inflammation in the nasal passage linings or sinuses leading to soft tissue growth known as nasal polyps.

The study met both main goals and showed that Nacula (mepolizumab), which is administered using a pre-filed syringe, when added to standard of care led to statistically significant improvements in both the size of nasal polyps and in nasal obstruction compared to the placebo arm, GlaxoSmithKline said.

Treatment options for the condition are currently limited and surgery to remove the polyp tissue may also be required for severe cases. However, polyps have a strong tendency to reoccur often leading to repeat surgery.

"These results show that Nucala can reduce symptoms and need for surgery in patients with nasal polyps," Chief Scientific Officer Hal Barron said.

(Reporting by Aakash Jagadeesh Babu in Bengaluru; Editing by Vinay Dwivedi)

((Aakash.B@thomsonreuters.com; within the U.S. +16462238780, outside the U.S. +91 80 67491576; Twitter: @JagadeeshAakash;))

The views and opinions expressed herein are the views and opinions of the author and do not necessarily reflect those of Nasdaq, Inc.

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