ContraVir Pharmaceuticals Inc ( CTRV ) stock jumped almost 28% after the company presented positive interim data for CMX157, an equivalent to tenofovir, to treat hepatitis B.
The head-to-head study is the first evaluation of CMX157 in HBV patients, and directly compares CMX157 to Gilead's ( GILD ) tenofovir disoproxil fumarate, known as Viread.
"We are pleased and excited with these clinical results, as they demonstrate CMX157's great potential in our ongoing effort to develop a cure for HBV," said CEO James Sapirstein. "The significant viral load reduction and favorable safety at this low dose of CMX157 speaks to the unique liver-targeting mechanism of our drug, which concentrates the antiviral activity of tenofovir in the liver, enabling anti-HBV efficacy at lower doses and minimal drug exposure to other tissues. We believe, based on the data that are being generated, that CMX157 has great potential as a safe and highly potent backbone of combination therapy against HBV."
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The views and opinions expressed herein are the views and opinions of the author and do not necessarily reflect those of Nasdaq, Inc.