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Aerie Reported Positive Phase III Data on Rhopressa

Aerie Pharmaceuticals, Inc.AERI announced positive results from a phase III study (Rocket 2) on Rhopressa, which is being evaluated for its ability in lowering intraocular pressure (IOP) in patients with glaucoma or ocular hypertension.

Both the once- and twice-daily dosages of Rhopressa achieved the primary efficacy endpoint demonstrating non inferiority compared to twice-daily Timoptic (timolol). Though the twice-daily dosage generated a higher incidence of adverse events, it was found to be slightly more effective than the once-daily dosage. Safety results from the study is expected at the end of 2015 or early 2016.

The phase III study on Rhopressa will be carried out in 4 parts - Rocket 1, Rocket 2, Rocket 3, and Rocket 4. Results from Rocket 1 study was announced in Apr 2015. Rocket 3 is currently in progress and the company expects to initiate Rocket 4 study later this month.

Aerie expects to submit a New Drug Application for Rhopressa in mid-2016.

Meanwhile, Aerie continues to progress on its pipeline. Currently, the company is evaluating Roclatan, a fixed-dose combination of Rhopressa and Xalatan (latanoprost) for the treatment of patients with glaucoma. Roclatan will be studied in three phase III studies - Mercury 1, Mercury 2, and Mercury 3. Mercury 1 is expected to be initiated later this month, followed by Mercury 2 study in 2016. The company expects to commence Mercury 3 in the second half of 2016.

Aerie carries a Zacks Rank #2 (Buy). Other favorably-ranked stocks in the health care sector include Gilead Sciences Inc. GILD , Medivation, Inc. MDVN and Regeneron Pharmaceuticals, Inc. REGN , each sporting a Zacks Rank #1 (Strong Buy).

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AERIE PHARMACT (AERI): Free Stock Analysis Report

REGENERON PHARM (REGN): Free Stock Analysis Report

GILEAD SCIENCES (GILD): Free Stock Analysis Report

MEDIVATION INC (MDVN): Free Stock Analysis Report

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The views and opinions expressed herein are the views and opinions of the author and do not necessarily reflect those of Nasdaq, Inc.


The views and opinions expressed herein are the views and opinions of the author and do not necessarily reflect those of Nasdaq, Inc.

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