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What's in Store for Sangamo (SGMO) This Earnings Season?


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Sangamo Therapeutics, Inc.SGMO is expected to report third-quarter 2018 results early next month.

The company has a mixed track record. Its metrics missed estimates in two of the last four quarters while surpassed the same in the remaining two with an average negative surprise of 37.74%. Last reported quarter, Sangamo lagged estimates with a negative surprise of 13.33%.

Shares of Sangamo have lost 19.8% year to date, in line with the industry's decrease.

Let's see, how things are shaping up for this announcement.

Factors to Consider

With no approved product in its portfolio at the moment, Sangamo primarily generates collaboration revenues from agreements with Pfizer PFE , Kite Pharma - a subsidiary of Gilead - and Bioverativ, a newly acquired unit of Sanofi.

Sangamo is developing SB-525, its gene therapy product candidate for hemophilia A, in partnership with Pfizer. In August, the company presented encouraging preliminary data from the phase I/II Alta study on SB-525 for treating hemophilia A. Sangamo and Pfizer expect to report detailed data from the study in the fourth quarter of 2018.

Sangamo's zinc finger nuclease (ZFN) in-vivo genome editing candidate is SB-913. It is currently being evaluated in a phase I/II CHAMPIONS study for the treatment of Mucopolysaccharidosis Type II (MPS II). In September 2018, the company presented 16-week data, which demonstrated reductions in urinary glycosaminoglycans (GAGs), a key biomarker of MPS II disease pathophysiology.

Another similar candidate, SB-318, is currently being examined in a phase I/II EMPOWERS study for treating MPS I.

Additionally, the gene-edited cell therapy candidate, ST-400, is currently being investigated in phase I/II Thales study for the treatment of patients with transfusion-dependent beta-thalassemia.

In February 2018, Sangamo signed a collaborative agreement with Kite Pharma, Inc., a subsidiary of Gilead, for developing gene-edited cell therapies to address cancer, using its ZFN technology platform.

Sangamo closed its previously announced acquisition of France's TxCell S.A., in October. Notably, TxCell develops innovative platforms for personalized T-cell immunotherapies for treating severe inflammatory and autoimmune diseases. The company expects the buyout to be a great strategic fit as it will expand its footprint in the field of CAR-Treg cell therapies for tackling such diseases.

Earnings Whispers

Our proven model does not conclusively show that Sangamo is likely to beat estimates this to-be-reported quarter. This is because a stock needs to have both a positive Earnings ESP and a solid Zacks Rank #1 (Strong Buy), 2 (Buy) or 3 (Hold) for this to happen. But that is not the case here as you will see below.

Earnings ESP: Sangamo has an Earnings ESP of 0.00%. This is because the Most Accurate Estimate and the Zacks Consensus Estimate are pegged at a loss of 13 cents each. You can uncover the best stocks to buy or sell before they're reported with our Earnings ESP Filter .

Zacks Rank:  Sangamo currently carries a Zacks Rank #3, which increases the predictive power of ESP. However, the company's 0.00% ESP makes surprise prediction difficult.

We caution against Sell-rated stocks (#4 or 5) going into an earnings announcement, especially when the company is seeing negative estimate revisions.

Sangamo Therapeutics, Inc. Price and EPS Surprise

Sangamo Therapeutics, Inc. Price and EPS Surprise | Sangamo Therapeutics, Inc. Quote



Stocks That Warrant a Look

Here are some biotech stocks that you may want to consider as per our model, these have the right combination of elements to beat on earnings this reporting season.

CRISPR Therapeutics AG CRSP is expected to release third-quarter results on Nov 14. The company has an Earnings ESP of +3.53% and a Zacks Rank of 1. You can see  the complete list of today's Zacks #1 Rank stocks here .

Emergent BioSolutions Inc. EBS has an Earnings ESP of +16.76% and a Zacks Rank #2. The company is scheduled to report third-quarter results on Nov 1.

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The views and opinions expressed herein are the views and opinions of the author and do not necessarily reflect those of Nasdaq, Inc.





This article appears in: Investing , Business , Earnings , Stocks
Referenced Symbols: PFE , EBS , SGMO , CRSP




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