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Annual Changes to the NASDAQ Biotechnology Index


NEW YORK, Dec. 14, 2018 (GLOBE NEWSWIRE) -- Nasdaq (Nasdaq:NDAQ) today announced the results of the annual re-ranking of the NASDAQ Biotechnology Index (Nasdaq:NBI), which will become effective prior to market open on Monday, December 24, 2018.

The following 60 securities will be added to the Index:

Nasdaq ACIU Ac Immune SA
Nasdaq ACRX AcelRx Pharmaceuticals, Inc.
Nasdaq ADVM Adverum Biotechnologies
Nasdaq AGLE Aeglea BioTherapeutics, Inc.
Nasdaq AKRX Akorn Inc.
Nasdaq ALLK Allakos Inc.
Nasdaq AMRS Amyris Inc.
Nasdaq APLS Apellis Pharma Inc.
Nasdaq APTX Aptinyx Inc.
Nasdaq AQST Aquestive Therapeutics
Nasdaq ARGX Argenx Se Ads
Nasdaq ARQL ArQule Inc.
Nasdaq AUTL Autolus Therapeutics Ltd.
Nasdaq CBAY CymaBay Therapeutics
Nasdaq CRNX Crinetics Pharmaceuticals
Nasdaq DCPH Deciphera Pharmaceuticals
Nasdaq DNLI Denali Therapeutics Inc.
Nasdaq DRNA Dicerna Pharmaceuticals Inc.
Nasdaq EIDX Eidos Therapeutics Inc.
Nasdaq EIGR Eiger BioPharma
Nasdaq ELOX Eloxx Pharman
Nasdaq EOLS Evolus Inc.
Nasdaq EYPT EyePoint Pharma Inc.
Nasdaq FATE Fate Therapeutics Inc.
Nasdaq FIXX Homology Medicines Inc.
Nasdaq FTSV Forty Seven Inc.
Nasdaq HCM Hutchison China MediTech
Nasdaq KNSA Kiniksa Pharma Ltd.
Nasdaq MGTA Magenta Therapeutics
Nasdaq MNOV Medicinova Inc.
Nasdaq MRTX Mirati Therapeutics Inc.
Nasdaq OCUL Ocular Therapeutix Inc.
Nasdaq OPTN OptiNose Inc.
Nasdaq PRQR ProQR Therapeutics N.V.
Nasdaq PTI Proteostasis Therapeutic
Nasdaq QTRX Quanterix Corporation
Nasdaq RCKT Rocket Pharmaceuticals
Nasdaq REPL Replimune Group Inc.
Nasdaq RUBY Rubius Therapeutics
Nasdaq RYTM Rhythm Pharmaceuticals
Nasdaq SIGA SIGA Technologies Inc.
Nasdaq SLDB Solid Biosciences Inc.
Nasdaq STIM Neuronetics, Inc.
Nasdaq SURF Surface Oncology Inc.
Nasdaq SYBX Synlogic Inc.
Nasdaq SYRS Syros Pharmaceuticals
Nasdaq TBIO Translate Bio Inc.
Nasdaq TCDA Tricida Inc.
Nasdaq TORC resTORbio Inc.
Nasdaq UBX Unity Biotechnology
Nasdaq UMRX Unum Therapeutics Inc.
Nasdaq URGN UroGen Pharma Ltd.
Nasdaq VSTM Verastem Inc.
Nasdaq WVE Wave Life Sciences
Nasdaq XENE Xenon Pharmaceuticals
Nasdaq XERS Xeris Pharmaceuticals
Nasdaq XON Intrexon Corporation
Nasdaq ZFGN Zafgen Inc.
Nasdaq ZLAB Zai Lab Ltd.

The Index is designed to track the performance of a set of securities listed on The Nasdaq Stock Market® (NASDAQ®) that are classified as either biotechnology or pharmaceutical according to the Industry Classification Benchmark (ICB).

As a result of the re-ranking, the following 26 securities will be removed from the Index:

Nasdaq AKAO Achaogen Inc.
Nasdaq ARDX Ardelyx Inc.
Nasdaq AVDL Avadel Pharmaceuticals PLC
Nasdaq BLCM Bellicum Pharmaceuticals
Nasdaq CALA Calithera Biosciences
Nasdaq CLDX Celldex Therapeutics, Inc.
Nasdaq CLXT Calyxt, Inc.
Nasdaq CMRX Chimerix, Inc.
Nasdaq CRIS Curis Inc.
Nasdaq CRVS Corvus Pharma
Nasdaq JNCE Jounce Therapeutics, Inc.
Nasdaq MRNS Marinus Pharmaceuticals
Nasdaq MRSN Mersana Therapeutics
Nasdaq NBRV Nabriva Therapeutics PLC
Nasdaq NEOS Neos Therapeutics Inc.
Nasdaq NH NantHealth Inc.
Nasdaq NK NantKwest Inc.
Nasdaq NLNK NewLink Genetics Corporation
Nasdaq RGEN Repligen Corporation
Nasdaq SGYP Synergy Pharmaceuticals Inc.
Nasdaq SHPG Shire PLC
Nasdaq SNDX Syndax Pharmaceuticals
Nasdaq SNNA Sienna Biopharmaceuticals
Nasdaq TLGT Teligent Inc.
Nasdaq TTPH Tetraphase Pharmaceuticals Inc.
Nasdaq VTL Vital Therapies Inc.

About Nasdaq Global Indexes

Nasdaq Global Indexes has been creating innovative, market-leading, transparent indexes since 1971. Today, our index offering spans geographies and asset classes and includes diverse families such as the Dividend and Income (includes Dividend Achievers), Dorsey Wright, Fixed Income (includes BulletShares®), Global Equity, Green Economy, Nordic and Commodity indexes. We continuously offer new opportunities for financial product sponsors across a wide-spectrum of investable products and for asset managers to measure risk and performance. Nasdaq also provides exchange listing, custom index and design solutions to financial organizations worldwide.

About Nasdaq

Nasdaq (Nasdaq: NDAQ) is a leading global provider of trading, clearing, exchange technology, listing, information and public company services. Through its diverse portfolio of solutions, Nasdaq enables customers to plan, optimize and execute their business vision with confidence, using proven technologies that provide transparency and insight for navigating today's global capital markets. As the creator of the world's first electronic stock market, its technology powers more than 100 marketplaces in 50 countries, and 1 in 10 of the world's securities transactions. Nasdaq is home to over 4,000 total listings with a market value of approximately $15 trillion. To learn more, visit

The information contained above is provided for informational and educational purposes only, and nothing contained herein should be construed as investment advice, either on behalf of a particular financial product or an overall investment strategy. Neither The NASDAQ OMX Group, Inc. nor any of its affiliates makes any recommendation to buy or sell any financial product or any representation about the financial condition of any company or fund. Statements regarding Nasdaq’s proprietary indexes are not guarantees of future performance. Actual results may differ materially from those expressed or implied. Past performance is not indicative of future results. Investors should undertake their own due diligence and carefully evaluate companies before investing. ADVICE FROM A SECURITIES PROFESSIONAL IS STRONGLY ADVISED.



Matthew Sheahan, Nasdaq

(212) 231-5945

Issuer & Investor Contact:

Natasha Selzer, Nasdaq

(301) 978-8623

Carla Proto, Nasdaq

(203) 926-3326

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