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Description:The SPDR S&P Biotech ETF seeks to replicate as closely as possible, before expenses, the performance of the S&P Biotechnology Select Industry Index (the "Index"). The Index represents the biotechnology sub-industry portion of the S&P Total Stock Market Index. The Index is one of nineteen (19) of the S&P Select Industry Indexes, each designed to measure the performance of a narrow sub-industry determined based on the Global Industry Classification Standards (GICS). The Index consists of the S&P Select Industry Indexes constituents belonging to the particular GICS sub-industry (e.g., biotechnology) that satisfy the following criteria: (i) rank within the 90th percentile of the float-adjusted market capitalization of the GICS sub-industry; (ii) are a U.S.-based company; and (iii) have a liquidity ratio greater than 60%. Under normal market conditions, the Fund generally invests substantially all, but at least 95%, of its total assets in the securities comprising the Index.
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| Top Holdings | ||
|---|---|---|
| ISIS | Isis Pharmaceuticals | 4.06% |
| NPSP | Nps Pharmaceuticals | 3.31% |
| ARNA | Arena Pharmaceuticals | 3.55% |
| SRPT | Sarepta Therapeutics Inc | 3.05% |
| INCY | Incyte Corp. | 3.5% |
| THRX | Theravance | 3.3% |
| SGEN | Seattle Genetics | 2.61% |
| SPPI | Spectrum Pharmaceuticals | 2.7% |
| PCYC | Pharmacyclics | 3.44% |
| CELG | Celgene Corp. | 3.27% |
| AMGN | Amgen Inc. | 2.61% |
| BIIB | Biogen Idec Inc | 2.61% |
| DVAX | Dynavax Technologies Corp. | 2.67% |
| REGN | Regeneron Pharmaceuticals | 2.57% |
| VRTX | Vertex Pharmaceuticals Inc. | 2.89% |
| KERX | Keryx Biopharmaceuticals | 2.55% |
| BMRN | Biomarin Pharmaceutical Inc. | 2.85% |
| DNDN | Dendreon Corp. | 2.83% |
| AFFY | Affymax | 2.9% |
| ALXN | Alexion Pharmaceuticals | 2.51% |
| ALKS | Alkermes | 2.62% |
| GILD | Gilead Sciences | 2.48% |
| IDIX | Idenix Pharmaceuticals | 2.86% |
| UTHR | United Therapeutics Corp. | 2.82% |
| ONXX | Onyx Pharmaceuticals | 2.45% |
Data is provided by Zacks Investment Research
