VHCP MANAGEMENT, LLC Information

3340 HILLVIEW AVENUE, PALO ALTO, California, 94304, (650) 475-3734

Report Date: 12/31/2014

Position Statistics

Total Positions 22
New Positions 4
Increased Positions 6
Decreased Positions 4
Positions with Activity 10
Sold Out Positions 2
Total Mkt Value (in $ millions) 375

Institutional Holdings information is filed by major institutions on form 13-F with the Securities and Exchange Commission.

Sector Weighting

Basic Materials
Capital Goods
Conglomerates
Consumer Cyclical
Consumer/Non-Cyclical
Energy
Financial
Healthcare 41.33%
Services 1.15%
Technology
Transportation
Utilities

22 Positions as of 12/31/2014

Company Class Value of Shares ($1,000s) ▲ Change in Value ($1,000s) Change (%) Shares Held
ALEXZA PHARMACEUTICALS INC COM NEW -150 Sold Out 0
NEUROCRINE BIOSCIENCES INC COM -11,852 Sold Out 0
RADIUS HEALTH INC COM (55.56) 233,294
SUNESIS PHARMACEUTICALS INC COM NEW 1,190 1,190 New 536,189
CYNAPSUS THERAPEUTICS INC COM NEW 1,675 1,675 New 1,536,750
OHR PHARMACEUTICAL INC COM NEW 3,668 New 477,000
OCERA THERAPEUTICS INC COM 3,973 New 703,730
THERAPEUTICSMD INC COM 4,292 New 846,500
LIPOCINE INC NEW COM 4,850 New 669,921
ZS PHARMA INC COM 4,947 New 100,000
STEMLINE THERAPEUTICS INC COM 5,414 4,335 401.97 356,400
FLAMEL TECHNOLOGIES SA SPONSORED ADR 7,825 New 500,000
HERON THERAPEUTICS INC COM 14,234 New 1,095,734
DYAX CORP COM 15,120 -15,113 (49.99) 1,000,659
BIOCRYST PHARMACEUTICALS COM 17,792 New 1,744,356
ZAFGEN INC COM 20,928 New 541,480
GW PHARMACEUTICALS PLC ADS 25,235 New 311,853
COHERUS BIOSCIENCES INC COM 27,492 27,492 New 870,269
DBV TECHNOLOGIES BOULOGNE BILL SHS NOM 32,713 6,073 22.80 693,810
AVALANCHE BIOTECHNOLOGIES INC COM 50,027 New 1,382,735