VHCP MANAGEMENT, LLC Information

3340 HILLVIEW AVENUE, PALO ALTO, California, 94304, (650) 475-3734

Report Date: 12/31/2013

Position Statistics

Total Positions 20
New Positions 2
Increased Positions 4
Decreased Positions 14
Positions with Activity 18
Sold Out Positions 3
Total Mkt Value (in $ millions) 192

Institutional Holdings information is filed by major institutions on form 13-F with the Securities and Exchange Commission.

Sector Weighting

Basic Materials
Capital Goods
Conglomerates
Consumer Cyclical
Consumer/Non-Cyclical
Energy
Financial
Healthcare 81.64%
Services 2.07%
Technology
Transportation
Utilities

20 Positions as of 12/31/2013

Company Class Value of Shares ($1,000s) ▲ Change in Value ($1,000s) Change (%) Shares Held
GTX INC DEL COM -680 Sold Out 0
OPHTHOTECH CORP COM -1,671 Sold Out 0
THRESHOLD PHARMACEUTICAL INC COM NEW -2,750 Sold Out 0
ALEXZA PHARMACEUTICALS INC COM NEW 1,537 -103 (6.25) 374,999
HYPERION THERAPEUTICS INC COM 2,728 -2,704 (49.78) 109,271
BIODEL INC COM NEW 2,872 -204 (6.64) 1,196,492
TESARO INC COM 3,521 -3,154 (47.25) 137,749
THERAPEUTICSMD INC COM 3,970 3,970 New 846,500
OCERA THERAPEUTICS INC COM 6,214 6,214 New 703,730
CHELSEA THERAPEUTICS INTL LTD COM 8,098 -3,883 (32.41) 1,701,170
NEUROCRINE BIOSCIENCES INC COM 9,617 -7,977 (45.34) 694,903
VANDA PHARMACEUTICALS INC COM 9,959 3,158 46.43 719,075
DBV TECHNOLOGIES BOULOGNE BILL SHS NOM 10,632 New 480,000
HERON THERAPEUTICS INC COM 12,305 7,214 141.68 1,095,735
KERYX BIOPHARMACEUTICALS INC COM 13,924 -14,595 (51.18) 1,000,273
BIOCRYST PHARMACEUTICALS COM 14,631 -3,555 (19.55) 1,754,356
DYAX CORP COM 17,591 -10,673 (37.76) 2,586,980
IRONWOOD PHARMACEUTICALS INC COM CL A 19,098 New 1,800,000
ANACOR PHARMACEUTICALS INC COM 23,762 -997 (4.03) 1,545,999
GW PHARMACEUTICALS PLC ADS 31,220 -6,179 (16.52) 699,376

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