VHCP MANAGEMENT, LLC Information

3340 HILLVIEW AVENUE, PALO ALTO, California, 94304, (650) 475-3734

Report Date: 12/31/2013

Position Statistics

Total Positions 20
New Positions 2
Increased Positions 4
Decreased Positions 14
Positions with Activity 18
Sold Out Positions 3
Total Mkt Value (in $ millions) 191

Institutional Holdings information is filed by major institutions on form 13-F with the Securities and Exchange Commission.

Sector Weighting

Basic Materials
Capital Goods
Conglomerates
Consumer Cyclical
Consumer/Non-Cyclical
Energy
Financial
Healthcare 81.76%
Services 2.1%
Technology
Transportation
Utilities

20 Positions as of 12/31/2013

Company ▲ Class Value of Shares ($1,000s) Change in Value ($1,000s) Change (%) Shares Held
ALEXZA PHARMACEUTICALS INC COM NEW 1,564 -104 (6.25) 374,999
ANACOR PHARMACEUTICALS INC COM 23,252 -975 (4.03) 1,545,999
BIOCRYST PHARMACEUTICALS COM 14,614 -3,551 (19.55) 1,754,356
BIODEL INC COM NEW 2,746 -195 (6.64) 1,196,492
CHELSEA THERAPEUTICS INTL LTD COM 7,927 -3,801 (32.41) 1,701,170
DBV TECHNOLOGIES BOULOGNE BILL SHS NOM 13,032 New 480,000
DYAX CORP COM 17,178 -10,422 (37.76) 2,586,980
GTX INC DEL COM -685 Sold Out 0
GW PHARMACEUTICALS PLC ADS 30,773 -6,091 (16.52) 699,376
HERON THERAPEUTICS INC COM 12,426 7,284 141.68 1,095,735
HYPERION THERAPEUTICS INC COM 2,688 -2,664 (49.78) 109,271
IRONWOOD PHARMACEUTICALS INC COM CL A 18,594 New 1,800,000
KERYX BIOPHARMACEUTICALS INC COM 13,914 -14,585 (51.18) 1,000,273
NEUROCRINE BIOSCIENCES INC COM 9,201 -7,632 (45.34) 694,903
OCERA THERAPEUTICS INC COM 5,799 5,799 New 703,730
OPHTHOTECH CORP COM -1,647 Sold Out 0
TESARO INC COM 3,462 -3,101 (47.25) 137,749
THERAPEUTICSMD INC COM 4,012 4,012 New 846,500
THRESHOLD PHARMACEUTICAL INC COM NEW -2,722 Sold Out 0
VANDA PHARMACEUTICALS INC COM 9,571 3,035 46.43 719,075

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