VHCP MANAGEMENT, LLC Information

3340 HILLVIEW AVENUE, PALO ALTO, California, 94304, (650) 475-3734

Report Date: 12/31/2013

Position Statistics

Total Positions 20
New Positions 2
Increased Positions 4
Decreased Positions 14
Positions with Activity 18
Sold Out Positions 3
Total Mkt Value (in $ millions) 192

Institutional Holdings information is filed by major institutions on form 13-F with the Securities and Exchange Commission.

Sector Weighting

Basic Materials
Capital Goods
Conglomerates
Consumer Cyclical
Consumer/Non-Cyclical
Energy
Financial
Healthcare 81%
Services 2.16%
Technology
Transportation
Utilities

20 Positions as of 12/31/2013

Company Class Value of Shares ($1,000s) Change in Value ($1,000s) ▲ Change (%) Shares Held
KERYX BIOPHARMACEUTICALS INC COM 13,464 -14,113 (51.18) 1,000,273
DYAX CORP COM 17,410 -10,563 (37.76) 2,586,980
NEUROCRINE BIOSCIENCES INC COM 9,346 -7,753 (45.34) 694,903
GW PHARMACEUTICALS PLC ADS 32,311 -6,395 (16.52) 699,376
CHELSEA THERAPEUTICS INTL LTD COM 8,047 -3,858 (32.41) 1,701,170
BIOCRYST PHARMACEUTICALS COM 14,631 -3,555 (19.55) 1,754,356
TESARO INC COM 3,451 -3,091 (47.25) 137,749
HYPERION THERAPEUTICS INC COM 2,700 -2,676 (49.78) 109,271
THRESHOLD PHARMACEUTICAL INC COM NEW -2,620 Sold Out 0
OPHTHOTECH CORP COM -1,668 Sold Out 0
ANACOR PHARMACEUTICALS INC COM 23,978 -1,006 (4.03) 1,545,999
GTX INC DEL COM -660 Sold Out 0
BIODEL INC COM NEW 2,848 -203 (6.64) 1,196,492
ALEXZA PHARMACEUTICALS INC COM NEW 1,549 -103 (6.25) 374,999
DBV TECHNOLOGIES BOULOGNE BILL SHS NOM 10,632 New 480,000
IRONWOOD PHARMACEUTICALS INC COM CL A 18,810 New 1,800,000
VANDA PHARMACEUTICALS INC COM 9,765 3,096 46.43 719,075
THERAPEUTICSMD INC COM 4,148 4,148 New 846,500
OCERA THERAPEUTICS INC COM 5,968 5,968 New 703,730
HERON THERAPEUTICS INC COM 12,798 7,503 141.68 1,095,735

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