TEKLA CAPITAL MANAGEMENT LLC Information

2 LIBERTY SQUARE, BOSTON, Massachusetts, 02109, (617) 772-8500

Report Date: 12/31/2013

Position Statistics

Total Positions 71
New Positions 10
Increased Positions 18
Decreased Positions 23
Positions with Activity 41
Sold Out Positions 14
Total Mkt Value (in $ millions) 938

Institutional Holdings information is filed by major institutions on form 13-F with the Securities and Exchange Commission.

Sector Weighting

Basic Materials
Capital Goods
Conglomerates 0%
Consumer Cyclical
Consumer/Non-Cyclical
Energy
Financial 6.04%
Healthcare 86.37%
Services 1.03%
Technology 3.15%
Transportation
Utilities

71 Positions as of 12/31/2013

Company Class Value of Shares ($1,000s) Change in Value ($1,000s) Change (%) Shares Held ▲
AEGERION PHARMACEUTICALS INC COM -516 Sold Out 0
AMARIN CORP PLC SPONS ADR NEW -2,199 Sold Out 0
ARIAD PHARMACEUTICALS INC COM -2,973 Sold Out 0
BAXTER INTL INC COM -5,656 Sold Out 0
CERES INC COM -175 Sold Out 0
ELAN PLC ADR -4,394 Sold Out 0
GENTIUM S P A SPONSORED ADR -3,621 Sold Out 0
ICAD INC COM NEW -753 Sold Out 0
MEDIVATION INC COM -5,341 Sold Out 0
MERCK & CO INC NEW COM -16,750 Sold Out 0
PERRIGO CO COM -31,540 Sold Out 0
QUESTCOR PHARMACEUTICALS INC COM -12,491 Sold Out 0
RAPTOR PHARMACEUTICAL CORP COM -905 Sold Out 0
SYNTA PHARMACEUTICALS CORP COM -1,944 Sold Out 0
WATERS CORP COM 1,078 1,078 New 9,700
THERMO FISHER SCIENTIFIC INC COM 1,191 1,191 New 9,980
PERKINELMER INC COM 1,164 1,164 New 26,300
MACROGENICS INC COM 638 638 New 31,857
CLOVIS ONCOLOGY INC COM 1,791 547 43.95 32,658
ALNYLAM PHARMACEUTICALS INC COM 2,623 1,344 105.08 48,695