TEKLA CAPITAL MANAGEMENT LLC Information

100 FEDERAL STREET, BOSTON, Massachusetts, 02110, (617) 772-8500

Report Date: 03/31/2015

Position Statistics

Total Positions 105
New Positions 19
Increased Positions 47
Decreased Positions 25
Positions with Activity 72
Sold Out Positions 8
Total Mkt Value (in $ millions) 2,484

Institutional Holdings information is filed by major institutions on form 13-F with the Securities and Exchange Commission.

Sector Weighting

Basic Materials
Capital Goods
Conglomerates 0.92%
Consumer Cyclical
Consumer/Non-Cyclical
Energy
Financial 3.82%
Healthcare 83.04%
Services 5.28%
Technology 2.97%
Transportation
Utilities

105 Positions as of 03/31/2015

Company ▲ Class Value of Shares ($1,000s) Change in Value ($1,000s) Change (%) Shares Held
ABBVIE INC COM 73,989 34,402 86.90 1,110,614
ACCELERATE DIAGNOSTICS INC COM 3,441 3,441 New 144,625
ACCURAY INC COM 4,523 New 731,943
ACHILLION PHARMACEUTICALS INC COM 5,150 5,150 New 547,300
ACORDA THERAPEUTICS INC COM 20,419 12,227 149.25 680,862
ACTAVIS PLC PFD CONV SER A 5,264 5,264 New 5,000
ACTAVIS PLC SHS 110,571 New 361,686
AEGERION PHARMACEUTICALS INC COM 3,994 3,994 New 206,000
AETNA INC NEW COM 38,945 New 331,931
AGIOS PHARMACEUTICALS INC COM 12,407 6,692 117.10 100,300
AKORN INC COM 39,679 New 849,482
ALERE INC COM 15,157 New 297,901
ALEXION PHARMACEUTICALS INC COM 82,333 4,131 5.28 502,305
ALKERMES PLC SHS 35,914 9,246 34.67 588,470
ALLSCRIPTS HEALTHCARE SOLUTNS COM 25,233 2,463 10.82 1,778,200
ALNYLAM PHARMACEUTICALS INC COM 17,097 9,009 111.37 130,195
AMGEN INC COM 55,032 -4,459 (7.49) 351,779
ATHENAHEALTH INC COM 2,667 2,667 New 23,100
BAXTER INTL INC COM 21,212 21,212 New 319,600
BELLICUM PHARMACEUTICALS INC COM 1,493 New 60,000