TEKLA CAPITAL MANAGEMENT LLC Information

2 LIBERTY SQUARE, BOSTON, Massachusetts, 02109, (617) 772-8500

Report Date: 03/31/2014

Position Statistics

Total Positions 63
New Positions 7
Increased Positions 20
Decreased Positions 16
Positions with Activity 36
Sold Out Positions 4
Total Mkt Value (in $ millions) 1,098

Institutional Holdings information is filed by major institutions on form 13-F with the Securities and Exchange Commission.

Sector Weighting

Basic Materials
Capital Goods
Conglomerates
Consumer Cyclical
Consumer/Non-Cyclical
Energy
Financial 5.27%
Healthcare 86.4%
Services 0.91%
Technology 3.35%
Transportation
Utilities

63 Positions as of 03/31/2014

Company Class ▲ Value of Shares ($1,000s) Change in Value ($1,000s) Change (%) Shares Held
TEVA PHARMACEUTICAL INDS LTD ADR 16,779 New 311,476
AVANIR PHARMACEUTICALS INC CL A NEW -2,253 Sold Out 0
ACCURAY INC COM 6,397 New 731,943
ACORDA THERAPEUTICS INC COM 3,500 New 112,881
AEGERION PHARMACEUTICALS INC COM 2,113 2,113 New 72,520
AETNA INC NEW COM 20,041 New 246,841
AKORN INC COM 23,157 -7,826 (25.26) 699,382
ALERE INC COM 10,823 -3,135 (22.46) 286,540
ALEXION PHARMACEUTICALS INC COM 55,262 -5,829 (9.54) 335,899
ALLERGAN INC COM 35,739 8,220 29.87 216,337
ALNYLAM PHARMACEUTICALS INC COM 3,605 755 26.49 61,595
AMGEN INC COM 53,752 4,472 9.08 449,543
AUXILIUM PHARMACEUTICALS INC COM 820 -2,545 (75.63) 42,165
BIODELIVERY SCIENCES INTL INC COM 9,525 1,414 17.43 683,260
BIOGEN IDEC INC COM 55,699 -5,763 (9.38) 173,983
BIOMARIN PHARMACEUTICAL INC COM 25,384 9,828 63.18 421,384
BLUEBIRD BIO INC COM 2,510 2,510 New 73,955
CATAMARAN CORP COM 10,035 3,692 58.22 231,000
CELGENE CORP COM 82,627 -6,652 (7.45) 944,092
CELLADON CORP COM 14,781 14,781 New 970,495