TEKLA CAPITAL MANAGEMENT LLC Information

2 LIBERTY SQUARE, BOSTON, Massachusetts, 02109, (617) 772-8500

Report Date: 12/31/2014

Position Statistics

Total Positions 94
New Positions 8
Increased Positions 24
Decreased Positions 31
Positions with Activity 55
Sold Out Positions 8
Total Mkt Value (in $ millions) 2,283

Institutional Holdings information is filed by major institutions on form 13-F with the Securities and Exchange Commission.

Sector Weighting

Basic Materials
Capital Goods
Conglomerates 0.37%
Consumer Cyclical
Consumer/Non-Cyclical
Energy
Financial 3.85%
Healthcare 85.6%
Services 4.6%
Technology 2.31%
Transportation
Utilities

94 Positions as of 12/31/2014

Company Class ▲ Value of Shares ($1,000s) Change in Value ($1,000s) Change (%) Shares Held
TEVA PHARMACEUTICAL INDS LTD ADR 26,254 -14,169 (35.05) 423,594
ABBVIE INC COM 34,257 6,514 23.48 594,219
ACCURAY INC COM 6,807 New 731,943
ACORDA THERAPEUTICS INC COM 9,342 New 273,162
AETNA INC NEW COM 35,649 -6,133 (14.68) 331,931
AGIOS PHARMACEUTICALS INC COM 4,463 1,082 32 46,200
AKORN INC COM 41,183 7,277 21.46 849,482
ALERE INC COM 14,353 New 297,901
ALEXION PHARMACEUTICALS INC COM 86,160 4,551 5.58 477,105
ALIGN TECHNOLOGY INC COM -3,804 Sold Out 0
ALLSCRIPTS HEALTHCARE SOLUTNS COM 18,982 18,982 New 1,604,600
ALNYLAM PHARMACEUTICALS INC COM 6,410 New 61,595
AMGEN INC COM 61,830 -21,098 (25.44) 380,279
BELLICUM PHARMACEUTICALS INC COM 1,348 1,348 New 60,000
BIODELIVERY SCIENCES INTL INC COM 3,937 -3,030 (43.49) 283,411
BIOGEN INC COM 140,689 60,397 75.22 327,283
BIOMARIN PHARMACEUTICAL INC COM 73,408 -18,094 (19.77) 570,027
BLUEBIRD BIO INC COM 6,238 -13,546 (68.47) 54,527
BRISTOL MYERS SQUIBB CO COM 34,930 New 535,240
CATAMARAN CORP COM 20,952 New 433,600