TEKLA CAPITAL MANAGEMENT LLC Information

2 LIBERTY SQUARE, BOSTON, Massachusetts, 02109, (617) 772-8500

Report Date: 06/30/2014

Position Statistics

Total Positions 66
New Positions 7
Increased Positions 19
Decreased Positions 15
Positions with Activity 34
Sold Out Positions 5
Total Mkt Value (in $ millions) 1,149

Institutional Holdings information is filed by major institutions on form 13-F with the Securities and Exchange Commission.

Sector Weighting

Basic Materials
Capital Goods
Conglomerates 0.16%
Consumer Cyclical
Consumer/Non-Cyclical
Energy
Financial 4.8%
Healthcare 88.53%
Services 0.94%
Technology 3.23%
Transportation
Utilities

66 Positions as of 06/30/2014

Company Class Value of Shares ($1,000s) Change in Value ($1,000s) Change (%) ▲ Shares Held
AUXILIUM PHARMACEUTICALS INC COM -1,315 Sold Out 0
MALLINCKRODT PUB LTD CO SHS -9,176 Sold Out 0
PHARMACYCLICS INC COM -6,804 Sold Out 0
PUMA BIOTECHNOLOGY INC COM -50,608 Sold Out 0
SUPERNUS PHARMACEUTICALS INC COM -1,187 Sold Out 0
AEGERION PHARMACEUTICALS INC COM 1 -2,443 (99.97) 20
PERRIGO CO PLC SHS 9,191 -15,319 (62.5) 62,952
ISHARES TR NASDQ BIOTEC ETF 17,794 -10,072 (36.14) 65,184
ALLERGAN INC COM 26,633 -10,153 (27.6) 156,627
BIODELIVERY SCIENCES INTL INC COM 8,657 -3,136 (26.59) 501,553
BLUEBIRD BIO INC COM 1,929 -687 (26.27) 54,527
MERRIMACK PHARMACEUTICALS INC COM 4,224 -1,408 (25) 567,787
SHIRE PLC SPONSORED ADR 32,124 -8,031 (20) 123,322
REGENERON PHARMACEUTICALS COM 69,474 -6,356 (8.38) 193,466
ACTAVIS PLC SHS 57,436 -2,888 (4.79) 242,254
ACCURAY INC COM 5,980 New 731,943
AKORN INC COM 25,562 New 699,382
ALERE INC COM 11,413 New 286,540
ALEXION PHARMACEUTICALS INC COM 54,258 New 335,899
ALNYLAM PHARMACEUTICALS INC COM 4,785 New 61,595