TEKLA CAPITAL MANAGEMENT LLC Information

2 LIBERTY SQUARE, BOSTON, Massachusetts, 02109, (617) 772-8500

Report Date: 12/31/2014

Position Statistics

Total Positions 94
New Positions 8
Increased Positions 24
Decreased Positions 31
Positions with Activity 55
Sold Out Positions 8
Total Mkt Value (in $ millions) 2,203

Institutional Holdings information is filed by major institutions on form 13-F with the Securities and Exchange Commission.

Sector Weighting

Basic Materials
Capital Goods
Conglomerates 0.35%
Consumer Cyclical
Consumer/Non-Cyclical
Energy
Financial 3.84%
Healthcare 85.71%
Services 4.63%
Technology 2.52%
Transportation
Utilities

94 Positions as of 12/31/2014

Company Class Value of Shares ($1,000s) Change in Value ($1,000s) ▲ Change (%) Shares Held
GILEAD SCIENCES INC COM 214,294 -42,205 (16.45) 2,080,731
IMPAX LABORATORIES INC COM 15,693 -29,394 (65.19) 344,683
ILLUMINA INC COM 19,422 -23,474 (54.72) 103,841
AMGEN INC COM 60,632 -20,689 (25.44) 380,279
INCYTE CORP COM 91,305 -20,036 (18) 936,461
THERMO FISHER SCIENTIFIC INC COM 15,324 -18,476 (54.66) 120,995
BIOMARIN PHARMACEUTICAL INC COM 64,937 -16,006 (19.77) 570,027
BLUEBIRD BIO INC COM 7,255 -15,754 (68.47) 54,527
TEVA PHARMACEUTICAL INDS LTD ADR 26,034 -14,050 (35.05) 423,594
CELLDEX THERAPEUTICS INC NEW COM -12,357 Sold Out 0
AMARIN CORP PLC SPONS ADR NEW -10,722 Sold Out 0
NEUROCRINE BIOSCIENCES INC COM 35,622 -10,028 (21.97) 1,000,350
UNITEDHEALTH GROUP INC COM -9,431 Sold Out 0
PFIZER INC COM 55,897 -9,008 (13.88) 1,638,241
PERKINELMER INC COM -8,475 Sold Out 0
CLOVIS ONCOLOGY INC COM 4 -8,291 (99.95) 51
SAGENT PHARMACEUTICALS INC COM 2,025 -7,559 (78.88) 85,500
ISHARES TR NASDQ BIOTEC ETF 19,492 -7,336 (27.35) 57,670
ENDO INTL PLC SHS 21,318 -7,150 (25.12) 251,773
AETNA INC NEW COM 35,583 -6,121 (14.68) 331,931


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