TEKLA CAPITAL MANAGEMENT LLC Information

2 LIBERTY SQUARE, BOSTON, Massachusetts, 02109, (617) 772-8500

Report Date: 06/30/2014

Position Statistics

Total Positions 66
New Positions 7
Increased Positions 19
Decreased Positions 15
Positions with Activity 34
Sold Out Positions 5
Total Mkt Value (in $ millions) 1,149

Institutional Holdings information is filed by major institutions on form 13-F with the Securities and Exchange Commission.

Sector Weighting

Basic Materials
Capital Goods
Conglomerates 0.15%
Consumer Cyclical
Consumer/Non-Cyclical
Energy
Financial 4.8%
Healthcare 88.64%
Services 0.9%
Technology 3.17%
Transportation
Utilities

66 Positions as of 06/30/2014

Company Class Value of Shares ($1,000s) Change in Value ($1,000s) ▲ Change (%) Shares Held
PUMA BIOTECHNOLOGY INC COM -48,228 Sold Out 0
PERRIGO CO PLC SHS 9,428 -15,713 (62.5) 62,952
ISHARES TR NASDQ BIOTEC ETF 17,766 -10,056 (36.14) 65,184
ALLERGAN INC COM 26,019 -9,919 (27.6) 156,627
MALLINCKRODT PUB LTD CO SHS -9,342 Sold Out 0
SHIRE PLC SPONSORED ADR 31,607 -7,902 (20) 123,322
PHARMACYCLICS INC COM -6,612 Sold Out 0
REGENERON PHARMACEUTICALS COM 69,632 -6,371 (8.38) 193,466
BIODELIVERY SCIENCES INTL INC COM 8,356 -3,027 (26.59) 501,553
ACTAVIS PLC SHS 57,080 -2,870 (4.79) 242,254
AEGERION PHARMACEUTICALS INC COM 1 -2,383 (99.97) 20
MERRIMACK PHARMACEUTICALS INC COM 4,071 -1,357 (25) 567,787
AUXILIUM PHARMACEUTICALS INC COM -1,315 Sold Out 0
SUPERNUS PHARMACEUTICALS INC COM -1,125 Sold Out 0
BLUEBIRD BIO INC COM 1,990 -709 (26.27) 54,527
ACCURAY INC COM 5,658 New 731,943
AKORN INC COM 25,437 New 699,382
ALERE INC COM 11,453 New 286,540
ALEXION PHARMACEUTICALS INC COM 53,606 New 335,899
ALNYLAM PHARMACEUTICALS INC COM 4,767 New 61,595