TEKLA CAPITAL MANAGEMENT LLC Information

2 LIBERTY SQUARE, BOSTON, Massachusetts, 02109, (617) 772-8500

Report Date: 09/30/2014

Position Statistics

Total Positions 90
New Positions 29
Increased Positions 66
Decreased Positions 2
Positions with Activity 68
Sold Out Positions 1
Total Mkt Value (in $ millions) 2,187

Institutional Holdings information is filed by major institutions on form 13-F with the Securities and Exchange Commission.

Sector Weighting

Basic Materials
Capital Goods
Conglomerates 0.18%
Consumer Cyclical
Consumer/Non-Cyclical
Energy
Financial 4.34%
Healthcare 86.66%
Services 3.54%
Technology 2.84%
Transportation
Utilities

90 Positions as of 09/30/2014

Company Class Value of Shares ($1,000s) ▼ Change in Value ($1,000s) Change (%) Shares Held
PERKINELMER INC COM 7,502 New 165,495
COMMUNITY HEALTH SYS INC NEW COM 7,437 7,437 New 154,672
AMARIN CORP PLC SPONS ADR NEW 7,393 6,076 461.53 5,643,412
BIODELIVERY SCIENCES INTL INC COM 7,167 New 501,553
BLUEBIRD BIO INC COM 7,144 4,891 217.14 172,927
HERON THERAPEUTICS INC COM 7,035 New 873,940
ENDOLOGIX INC COM 6,943 6,943 New 551,000
WELLCARE HEALTH PLANS INC COM 6,240 6,240 New 88,652
CENTENE CORP DEL COM 5,902 New 60,000
ALNYLAM PHARMACEUTICALS INC COM 5,649 New 61,595
SAREPTA THERAPEUTICS INC COM 5,433 5,433 New 345,400
ACCURAY INC COM 5,277 New 731,943
MERRIMACK PHARMACEUTICALS INC COM 5,127 New 567,787
CLOVIS ONCOLOGY INC COM 5,057 2,755 119.68 104,051
NEKTAR THERAPEUTICS COM 4,912 4,912 New 334,800
KARYOPHARM THERAPEUTICS INC COM 4,202 4,202 New 101,966
KYTHERA BIOPHARMACEUTICALS INC COM 3,986 2,233 127.41 111,433
INTELLIPHARMACEUTICS INTL INC COM 3,931 New 1,404,000
ALIGN TECHNOLOGY INC COM 3,918 3,918 New 70,400
LIGAND PHARMACEUTICALS INC COM NEW 3,671 3,671 New 69,200


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