TEKLA CAPITAL MANAGEMENT LLC Information

2 LIBERTY SQUARE, BOSTON, Massachusetts, 02109, (617) 772-8500

Report Date: 12/31/2014

Position Statistics

Total Positions 95
New Positions 8
Increased Positions 24
Decreased Positions 31
Positions with Activity 55
Sold Out Positions 8
Total Mkt Value (in $ millions) 2,263

Institutional Holdings information is filed by major institutions on form 13-F with the Securities and Exchange Commission.

Sector Weighting

Basic Materials
Capital Goods
Conglomerates 0.32%
Consumer Cyclical
Consumer/Non-Cyclical
Energy
Financial 3.7%
Healthcare 85.74%
Services 4.7%
Technology 2.35%
Transportation
Utilities

95 Positions as of 12/31/2014

Company Class Value of Shares ($1,000s) ▼ Change in Value ($1,000s) Change (%) Shares Held
LILLY ELI & CO COM 13,116 New 186,918
IRONWOOD PHARMACEUTICALS INC COM CL A 11,866 New 768,050
SANGAMO BIOSCIENCES INC COM 11,422 -1,194 (9.47) 679,100
HERON THERAPEUTICS INC COM 11,352 New 873,940
CELLADON CORP COM 11,008 -6,607 (37.51) 606,482
LTC PPTYS INC COM 10,560 New 236,618
HCA HOLDINGS INC COM 10,551 2,275 27.49 147,488
PERRIGO CO PLC SHS 9,724 New 62,952
ZIMMER HLDGS INC COM 9,607 New 79,800
ACORDA THERAPEUTICS INC COM 9,244 New 273,162
SENIOR HSG PPTYS TR SH BEN INT 9,152 New 409,504
STRYKER CORP COM 9,081 New 95,840
CIGNA CORPORATION COM 9,031 -5,838 (39.26) 74,251
IDEXX LABS INC COM 8,824 New 56,265
ENDOLOGIX INC COM 8,689 New 551,000
VERASTEM INC COM 8,555 New 1,149,827
PTC THERAPEUTICS INC COM 8,499 2,853 50.54 119,150
ST JUDE MED INC COM 8,169 New 122,510
WELLCARE HEALTH PLANS INC COM 8,050 New 88,652
COMMUNITY HEALTH SYS INC NEW COM 7,505 New 154,672