TEKLA CAPITAL MANAGEMENT LLC Information

100 FEDERAL STREET, BOSTON, Massachusetts, 02110, (617) 772-8500

Report Date: 03/31/2015

Position Statistics

Total Positions 105
New Positions 19
Increased Positions 47
Decreased Positions 25
Positions with Activity 72
Sold Out Positions 8
Total Mkt Value (in $ millions) 2,486

Institutional Holdings information is filed by major institutions on form 13-F with the Securities and Exchange Commission.

Sector Weighting

Basic Materials
Capital Goods
Conglomerates 0.94%
Consumer Cyclical
Consumer/Non-Cyclical
Energy
Financial 3.86%
Healthcare 83.04%
Services 5.26%
Technology 2.97%
Transportation
Utilities

19 New Positions as of 03/31/2015

Company Class Value of Shares ($1,000s) ▼ Change in Value ($1,000s) Change (%) Shares Held
BAXTER INTL INC COM 21,289 21,289 New 319,600
HEALTH CARE REIT INC PFD PER CON I 12,622 12,622 New 200,000
MERCK & CO INC NEW COM 11,265 11,265 New 185,000
THERAPEUTICSMD INC COM 10,489 10,489 New 1,481,500
TROVAGENE INC COM NEW 7,124 7,124 New 650,000
ACHILLION PHARMACEUTICALS INC COM 5,413 5,413 New 547,300
ACTAVIS PLC PFD CONV SER A 5,287 5,287 New 5,000
ZOGENIX INC COM 4,846 4,846 New 2,850,811
FLEX PHARMA INC COM 4,152 4,152 New 232,600
AEGERION PHARMACEUTICALS INC COM 4,013 4,013 New 206,000
INTRA CELLULAR THERAPIES INC COM 3,938 3,938 New 150,000
EPIZYME INC COM 3,794 3,794 New 200,000
ACCELERATE DIAGNOSTICS INC COM 3,228 3,228 New 144,625
TENET HEALTHCARE CORP COM NEW 3,165 3,165 New 59,500
ATHENAHEALTH INC COM 2,693 2,693 New 23,100
KITE PHARMA INC COM 2,564 2,564 New 46,500
IMMUNOMEDICS INC COM 1,930 1,930 New 500,000
CELLECTIS S A SPONSORED ADS 1,716 1,716 New 40,000
XENCOR INC COM 363 363 New 20,000