TEKLA CAPITAL MANAGEMENT LLC Information

2 LIBERTY SQUARE, BOSTON, Massachusetts, 02109, (617) 772-8500

Report Date: 03/31/2014

Position Statistics

Total Positions 63
New Positions 7
Increased Positions 20
Decreased Positions 16
Positions with Activity 36
Sold Out Positions 4
Total Mkt Value (in $ millions) 1,120

Institutional Holdings information is filed by major institutions on form 13-F with the Securities and Exchange Commission.

Sector Weighting

Basic Materials
Capital Goods
Conglomerates
Consumer Cyclical
Consumer/Non-Cyclical
Energy
Financial 5.19%
Healthcare 86.7%
Services 0.92%
Technology 3.3%
Transportation
Utilities

7 New Positions as of 03/31/2014

Company Class Value of Shares ($1,000s) ▼ Change in Value ($1,000s) Change (%) Shares Held
CELLADON CORP COM 12,209 12,209 New 970,495
QUESTCOR PHARMACEUTICALS INC COM 11,111 11,111 New 117,080
HERON THERAPEUTICS INC COM 6,381 6,381 New 696,597
BLUEBIRD BIO INC COM 2,469 2,469 New 73,955
PTC THERAPEUTICS INC COM 2,200 2,200 New 79,150
AEGERION PHARMACEUTICALS INC COM 2,176 2,176 New 72,520
SANGAMO BIOSCIENCES INC COM 584 584 New 47,400