TEKLA CAPITAL MANAGEMENT LLC Information

100 FEDERAL STREET, BOSTON, Massachusetts, 02110, (617) 772-8500

Report Date: 06/30/2015

Position Statistics

Total Positions 115
New Positions 18
Increased Positions 32
Decreased Positions 26
Positions with Activity 58
Sold Out Positions 11
Total Mkt Value (in $ millions) 2,481

Institutional Holdings information is filed by major institutions on form 13-F with the Securities and Exchange Commission.

Sector Weighting

Basic Materials
Capital Goods
Conglomerates 1.33%
Consumer Cyclical
Consumer/Non-Cyclical
Energy
Financial 4.61%
Healthcare 82.69%
Services 3.76%
Technology 3.59%
Transportation
Utilities

18 New Positions as of 06/30/2015

Company Class Value of Shares ($1,000s) ▼ Change in Value ($1,000s) Change (%) Shares Held
HUMANA INC COM 20,242 20,242 New 112,000
PARATEK PHARMACEUTICALS INC COM 17,082 17,082 New 691,000
ACADIA PHARMACEUTICALS COM 13,461 13,461 New 370,000
PIERIS PHARMACEUTICALS INC COM 10,506 10,506 New 3,848,191
AURIS MED HLDG AG COM 10,042 10,042 New 2,105,263
ESPERION THERAPEUTICS INC NEW COM 7,822 7,822 New 148,000
ALLIQUA BIOMEDICAL INC COM NEW 6,930 6,930 New 1,650,000
ULTRAGENYX PHARMACEUTICAL INC COM 6,444 6,444 New 60,000
MEDIVATION INC COM 4,817 4,817 New 53,700
ISIS PHARMACEUTICALS INC COM 4,814 4,814 New 98,200
FOAMIX PHARMACEUTICALS LTD SHS 4,001 4,001 New 413,800
DERMIRA INC COM 2,438 2,438 New 97,197
GENMARK DIAGNOSTICS INC COM 2,035 2,035 New 215,149
GALAPAGOS NV SPON ADR 1,232 1,232 New 20,000
ABAXIS INC COM 1,055 1,055 New 22,466
TRILLIUM THERAPEUTICS INC COM NEW 974 974 New 65,000
CIDARA THERAPEUTICS INC COM 713 713 New 50,000
ADAPTIMMUNE THERAPEUTICS PLC SPONDS ADR 315 315 New 27,500