TEKLA CAPITAL MANAGEMENT LLC Information

2 LIBERTY SQUARE, BOSTON, Massachusetts, 02109, (617) 772-8500

Report Date: 03/31/2014

Position Statistics

Total Positions 63
New Positions 7
Increased Positions 20
Decreased Positions 16
Positions with Activity 36
Sold Out Positions 4
Total Mkt Value (in $ millions) 1,137

Institutional Holdings information is filed by major institutions on form 13-F with the Securities and Exchange Commission.

Sector Weighting

Basic Materials
Capital Goods
Conglomerates
Consumer Cyclical
Consumer/Non-Cyclical
Energy
Financial 5.04%
Healthcare 86.97%
Services 0.93%
Technology 3.2%
Transportation
Utilities

20 INCREASED Positions as of 03/31/2014

Company Class Value of Shares ($1,000s) ▼ Change in Value ($1,000s) Change (%) Shares Held
AMGEN INC COM 58,445 4,862 9.08 449,543
ALLERGAN INC COM 37,247 8,567 29.87 216,337
MYLAN INC COM 32,969 8,290 33.59 652,209
BIOMARIN PHARMACEUTICAL INC COM 25,742 9,966 63.18 421,384
MCKESSON CORP COM 12,979 2,104 19.35 67,862
CELLADON CORP COM 12,578 12,578 New 970,495
QUESTCOR PHARMACEUTICALS INC COM 10,812 10,812 New 117,080
CATAMARAN CORP COM 10,610 3,904 58.22 231,000
SAGENT PHARMACEUTICALS INC COM 10,503 2,219 26.78 404,731
BIODELIVERY SCIENCES INTL INC COM 9,169 1,361 17.43 683,260
PERKINELMER INC COM 7,801 6,562 529.26 165,495
THERMO FISHER SCIENTIFIC INC COM 7,440 6,196 497.80 59,660
HERON THERAPEUTICS INC COM 6,506 6,506 New 696,597
ALNYLAM PHARMACEUTICALS INC COM 3,421 716 26.49 61,595
AEGERION PHARMACEUTICALS INC COM 2,585 2,585 New 72,520
BLUEBIRD BIO INC COM 2,544 2,544 New 73,955
NPS PHARMACEUTICALS INC COM 2,428 589 32.01 82,900
PTC THERAPEUTICS INC COM 2,295 2,295 New 79,150
CLOVIS ONCOLOGY INC COM 1,823 566 45.03 47,364
SANGAMO BIOSCIENCES INC COM 594 594 New 47,400

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