TEKLA CAPITAL MANAGEMENT LLC Information

100 FEDERAL STREET, BOSTON, Massachusetts, 02110, (617) 772-8500

Report Date: 06/30/2015

Position Statistics

Total Positions 114
New Positions 18
Increased Positions 32
Decreased Positions 26
Positions with Activity 58
Sold Out Positions 11
Total Mkt Value (in $ millions) 2,515

Institutional Holdings information is filed by major institutions on form 13-F with the Securities and Exchange Commission.

Sector Weighting

Basic Materials
Capital Goods
Conglomerates 0.17%
Consumer Cyclical
Consumer/Non-Cyclical
Energy
Financial 4.63%
Healthcare 83.71%
Services 3.76%
Technology 3.64%
Transportation
Utilities

32 INCREASED Positions as of 06/30/2015

Company Class Value of Shares ($1,000s) ▼ Change in Value ($1,000s) Change (%) Shares Held
VERTEX PHARMACEUTICALS INC COM 120,364 58,132 93.41 897,903
BIOGEN INC COM 107,273 4,176 4.05 353,233
MYLAN N V SHS EURO 92,530 41,651 81.86 1,837,005
TEVA PHARMACEUTICAL INDS LTD ADR 90,235 25,362 39.09 1,387,594
JOHNSON & JOHNSON COM 84,189 42,827 103.54 884,612
AMGEN INC COM 77,521 22,682 41.36 497,280
ALKERMES PLC SHS 65,390 28,228 75.96 1,035,470
ILLUMINA INC COM 46,319 19,444 72.35 229,641
ENDO INTL PLC SHS 25,646 5,832 29.43 325,873
HUMANA INC COM 20,609 20,609 New 112,000
HCA HOLDINGS INC COM 18,989 5,889 44.95 213,788
PARATEK PHARMACEUTICALS INC COM 18,415 18,415 New 691,000
ACADIA PHARMACEUTICALS COM 14,123 14,123 New 370,000
PIERIS PHARMACEUTICALS INC COM 11,083 11,083 New 3,848,191
AURIS MED HLDG AG COM 10,232 10,232 New 2,105,263
IDEXX LABS INC COM 9,689 1,451 17.62 132,352
ZOGENIX INC COM NEW 8,747 2,186 33.32 475,101
TENET HEALTHCARE CORP COM NEW 8,278 5,284 176.47 164,500
ESPERION THERAPEUTICS INC NEW COM 7,771 7,771 New 148,000
ALLIQUA BIOMEDICAL INC COM NEW 7,260 7,260 New 1,650,000


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