TEKLA CAPITAL MANAGEMENT LLC Information

2 LIBERTY SQUARE, BOSTON, Massachusetts, 02109, (617) 772-8500

Report Date: 12/31/2014

Position Statistics

Total Positions 95
New Positions 8
Increased Positions 24
Decreased Positions 31
Positions with Activity 55
Sold Out Positions 8
Total Mkt Value (in $ millions) 2,285

Institutional Holdings information is filed by major institutions on form 13-F with the Securities and Exchange Commission.

Sector Weighting

Basic Materials
Capital Goods
Conglomerates 0.31%
Consumer Cyclical
Consumer/Non-Cyclical
Energy
Financial 3.68%
Healthcare 83.19%
Services 4.68%
Technology 2.35%
Transportation
Utilities

24 INCREASED Positions as of 12/31/2014

Company Class Value of Shares ($1,000s) ▼ Change in Value ($1,000s) Change (%) Shares Held
BIOGEN IDEC INC COM 136,081 58,418 75.22 327,283
ALEXION PHARMACEUTICALS INC COM 88,083 4,652 5.58 477,105
REGENERON PHARMACEUTICALS COM 83,004 4,687 5.98 198,366
SHIRE PLC SPONSORED ADR 66,557 37,402 128.28 281,522
AKORN INC COM 45,626 8,062 21.46 849,482
ABBVIE INC COM 35,926 6,832 23.48 594,219
JAZZ PHARMACEUTICALS PLC SHS USD 35,118 4,901 16.22 201,341
VENTAS INC COM 21,865 11,680 114.68 292,782
ALLSCRIPTS HEALTHCARE SOLUTNS COM 19,849 19,849 New 1,604,600
PHYSICIANS RLTY TR COM 15,903 4,753 42.62 958,002
OMEGA HEALTHCARE INVS INC COM 15,260 5,019 49.01 376,416
MEDICAL PPTYS TRUST INC COM 14,819 5,322 56.04 978,774
SABRA HEALTH CARE REIT INC COM 13,448 2,127 18.78 407,890
HCA HOLDINGS INC COM 10,618 2,289 27.49 147,488
PTC THERAPEUTICS INC COM 8,375 2,812 50.54 119,150
ELEVEN BIOTHERAPEUTICS INC COM 6,932 6,932 New 610,200
AGIOS PHARMACEUTICALS INC COM 4,985 1,208 32 46,200
WRIGHT MED GROUP INC COM 3,945 3,945 New 156,100
DICERNA PHARMACEUTICALS INC COM 3,845 3,845 New 156,250
KARYOPHARM THERAPEUTICS INC COM 3,808 990 35.11 137,766


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