TEKLA CAPITAL MANAGEMENT LLC Information

2 LIBERTY SQUARE, BOSTON, Massachusetts, 02109, (617) 772-8500

Report Date: 06/30/2014

Position Statistics

Total Positions 66
New Positions 7
Increased Positions 19
Decreased Positions 15
Positions with Activity 34
Sold Out Positions 5
Total Mkt Value (in $ millions) 1,136

Institutional Holdings information is filed by major institutions on form 13-F with the Securities and Exchange Commission.

Sector Weighting

Basic Materials
Capital Goods
Conglomerates 0.14%
Consumer Cyclical
Consumer/Non-Cyclical
Energy
Financial 4.71%
Healthcare 88.98%
Services 0.82%
Technology 3.03%
Transportation
Utilities

15 DECREASED Positions as of 06/30/2014

Company Class Value of Shares ($1,000s) ▼ Change in Value ($1,000s) Change (%) Shares Held
REGENERON PHARMACEUTICALS COM 70,833 -6,480 (8.38) 193,466
ACTAVIS PLC SHS 54,912 -2,761 (4.79) 242,254
ALLERGAN INC COM 28,075 -10,703 (27.6) 156,627
SHIRE PLC SPONSORED ADR 22,764 -5,691 (20) 123,322
ISHARES TR NASDQ BIOTEC ETF 17,573 -9,947 (36.14) 65,184
PERRIGO CO PLC SHS 9,346 -15,578 (62.5) 62,952
BIODELIVERY SCIENCES INTL INC COM 8,396 -3,042 (26.59) 501,553
MERRIMACK PHARMACEUTICALS INC COM 4,928 -1,643 (25) 567,787
BLUEBIRD BIO INC COM 2,008 -715 (26.27) 54,527
AEGERION PHARMACEUTICALS INC COM 1 -2,314 (99.97) 20
AUXILIUM PHARMACEUTICALS INC COM -1,290 Sold Out 0
MALLINCKRODT PUB LTD CO SHS -9,153 Sold Out 0
PHARMACYCLICS INC COM -6,330 Sold Out 0
PUMA BIOTECHNOLOGY INC COM -41,908 Sold Out 0
SUPERNUS PHARMACEUTICALS INC COM -1,097 Sold Out 0