TEKLA CAPITAL MANAGEMENT LLC Information

2 LIBERTY SQUARE, BOSTON, Massachusetts, 02109, (617) 772-8500

Report Date: 06/30/2014

Position Statistics

Total Positions 66
New Positions 7
Increased Positions 19
Decreased Positions 15
Positions with Activity 34
Sold Out Positions 5
Total Mkt Value (in $ millions) 1,146

Institutional Holdings information is filed by major institutions on form 13-F with the Securities and Exchange Commission.

Sector Weighting

Basic Materials
Capital Goods
Conglomerates 0.15%
Consumer Cyclical
Consumer/Non-Cyclical
Energy
Financial 4.8%
Healthcare 88.58%
Services 0.96%
Technology 3.21%
Transportation
Utilities

15 DECREASED Positions as of 06/30/2014

Company Class Value of Shares ($1,000s) ▼ Change in Value ($1,000s) Change (%) Shares Held
REGENERON PHARMACEUTICALS COM 68,771 -6,292 (8.38) 193,466
ACTAVIS PLC SHS 57,841 -2,909 (4.79) 242,254
SHIRE PLC SPONSORED ADR 31,929 -7,982 (20) 123,322
ALLERGAN INC COM 26,658 -10,163 (27.6) 156,627
ISHARES TR NASDQ BIOTEC ETF 17,653 -9,992 (36.14) 65,184
PERRIGO CO PLC SHS 9,144 -15,241 (62.5) 62,952
BIODELIVERY SCIENCES INTL INC COM 8,642 -3,131 (26.59) 501,553
MERRIMACK PHARMACEUTICALS INC COM 4,156 -1,385 (25) 567,787
BLUEBIRD BIO INC COM 1,934 -689 (26.27) 54,527
AEGERION PHARMACEUTICALS INC COM 1 -2,350 (99.97) 20
AUXILIUM PHARMACEUTICALS INC COM -907 Sold Out 0
MALLINCKRODT PUB LTD CO SHS -9,125 Sold Out 0
PHARMACYCLICS INC COM -6,735 Sold Out 0
PUMA BIOTECHNOLOGY INC COM -50,811 Sold Out 0
SUPERNUS PHARMACEUTICALS INC COM -1,162 Sold Out 0