TEKLA CAPITAL MANAGEMENT LLC Information

2 LIBERTY SQUARE, BOSTON, Massachusetts, 02109, (617) 772-8500

Report Date: 06/30/2014

Position Statistics

Total Positions 66
New Positions 7
Increased Positions 19
Decreased Positions 15
Positions with Activity 34
Sold Out Positions 5
Total Mkt Value (in $ millions) 1,129

Institutional Holdings information is filed by major institutions on form 13-F with the Securities and Exchange Commission.

Sector Weighting

Basic Materials
Capital Goods
Conglomerates 0.15%
Consumer Cyclical
Consumer/Non-Cyclical
Energy
Financial 4.68%
Healthcare 88.56%
Services 0.96%
Technology 3.13%
Transportation
Utilities

34 Activity Positions as of 06/30/2014

Company Class Value of Shares ($1,000s) ▼ Change in Value ($1,000s) Change (%) Shares Held
REGENERON PHARMACEUTICALS COM 67,092 -6,138 (8.38) 193,466
ACTAVIS PLC SHS 54,042 -2,718 (4.79) 242,254
VERTEX PHARMACEUTICALS INC COM 49,724 3,785 8.24 540,944
INCYTE CORP COM 40,041 10,953 37.66 768,238
SHIRE PLC SPONSORED ADR 30,269 -7,567 (20) 123,322
ALLERGAN INC COM 25,345 -9,662 (27.6) 156,627
AETNA INC NEW COM 19,585 55 .28 247,541
CUBIST PHARMACEUTICALS INC COM 17,467 2,450 16.32 263,772
ISHARES TR NASDQ BIOTEC ETF 17,419 -9,860 (36.14) 65,184
JAZZ PHARMACEUTICALS PLC SHS USD 15,053 15,053 New 95,957
NEUROCRINE BIOSCIENCES INC COM 12,320 5,653 84.79 790,490
ALKERMES PLC SHS 11,273 2,691 31.35 255,970
BRISTOL MYERS SQUIBB CO COM 10,191 10,191 New 202,600
PFIZER INC COM 9,694 9,694 New 334,957
PERRIGO CO PLC SHS 9,496 -15,826 (62.5) 62,952
MOLINA HEALTHCARE INC COM 8,920 4,513 102.42 212,541
HERON THERAPEUTICS INC COM 8,093 1,642 25.46 873,940
INFINITY PHARMACEUTICALS INC COM 7,332 3,563 94.56 680,746
ACORDA THERAPEUTICS INC COM 7,157 3,578 100 225,762
BIODELIVERY SCIENCES INTL INC COM 7,027 -2,546 (26.59) 501,553