TEKLA CAPITAL MANAGEMENT LLC Information

2 LIBERTY SQUARE, BOSTON, Massachusetts, 02109, (617) 772-8500

Report Date: 06/30/2014

Position Statistics

Total Positions 66
New Positions 7
Increased Positions 19
Decreased Positions 15
Positions with Activity 34
Sold Out Positions 5
Total Mkt Value (in $ millions) 1,161

Institutional Holdings information is filed by major institutions on form 13-F with the Securities and Exchange Commission.

Sector Weighting

Basic Materials
Capital Goods
Conglomerates 0.15%
Consumer Cyclical
Consumer/Non-Cyclical
Energy
Financial 4.78%
Healthcare 88.7%
Services 0.91%
Technology 3.14%
Transportation
Utilities

34 Activity Positions as of 06/30/2014

Company Class Value of Shares ($1,000s) ▼ Change in Value ($1,000s) Change (%) Shares Held
REGENERON PHARMACEUTICALS COM 69,439 -6,353 (8.38) 193,466
ACTAVIS PLC SHS 58,579 -2,946 (4.79) 242,254
VERTEX PHARMACEUTICALS INC COM 56,123 4,272 8.24 540,944
INCYTE CORP COM 37,889 10,365 37.66 768,238
SHIRE PLC SPONSORED ADR 31,838 -7,960 (20) 123,322
ALLERGAN INC COM 26,346 -10,044 (27.6) 156,627
AETNA INC NEW COM 20,717 59 .28 247,541
ISHARES TR NASDQ BIOTEC ETF 17,941 -10,155 (36.14) 65,184
CUBIST PHARMACEUTICALS INC COM 17,554 2,462 16.32 263,772
JAZZ PHARMACEUTICALS PLC SHS USD 15,702 15,702 New 95,957
NEUROCRINE BIOSCIENCES INC COM 12,664 5,810 84.79 790,490
ALKERMES PLC SHS 11,961 2,855 31.35 255,970
BRISTOL MYERS SQUIBB CO COM 10,436 10,436 New 202,600
PFIZER INC COM 10,183 10,183 New 334,957
MOLINA HEALTHCARE INC COM 9,566 4,840 102.42 212,541
INFINITY PHARMACEUTICALS INC COM 9,496 4,615 94.56 680,746
PERRIGO CO PLC SHS 9,271 -15,452 (62.5) 62,952
BIODELIVERY SCIENCES INTL INC COM 8,536 -3,093 (26.59) 501,553
HERON THERAPEUTICS INC COM 7,595 1,541 25.46 873,940
UNITEDHEALTH GROUP INC COM 7,304 66 .91 83,186