TEKLA CAPITAL MANAGEMENT LLC Information

2 LIBERTY SQUARE, BOSTON, Massachusetts, 02109, (617) 772-8500

Report Date: 03/31/2014

Position Statistics

Total Positions 63
New Positions 7
Increased Positions 20
Decreased Positions 16
Positions with Activity 36
Sold Out Positions 4
Total Mkt Value (in $ millions) 1,097

Institutional Holdings information is filed by major institutions on form 13-F with the Securities and Exchange Commission.

Sector Weighting

Basic Materials
Capital Goods
Conglomerates
Consumer Cyclical
Consumer/Non-Cyclical
Energy
Financial 5.28%
Healthcare 86.58%
Services 0.93%
Technology 3.38%
Transportation
Utilities

36 Activity Positions as of 03/31/2014

Company Class Value of Shares ($1,000s) ▼ Change in Value ($1,000s) Change (%) Shares Held
CELGENE CORP COM 84,204 -6,778 (7.45) 944,092
REGENERON PHARMACEUTICALS COM 66,752 -15,658 (19) 211,166
BIOGEN IDEC INC COM 56,061 -5,800 (9.38) 173,983
ALEXION PHARMACEUTICALS INC COM 54,822 -5,783 (9.54) 335,899
AMGEN INC COM 53,842 4,479 9.08 449,543
ALLERGAN INC COM 36,005 8,282 29.87 216,337
MYLAN INC COM 32,741 8,233 33.59 652,209
INCYTE CORP COM 28,364 -1,536 (5.14) 558,080
ISHARES NASDQ BIOTEC ETF 26,210 -8,737 (25) 102,080
BIOMARIN PHARMACEUTICAL INC COM 24,984 9,673 63.18 421,384
PERRIGO CO PLC SHS 24,535 -7,782 (24.08) 167,874
AKORN INC COM 24,220 -8,186 (25.26) 699,382
MCKESSON CORP COM 12,824 2,079 19.35 67,862
CELLADON CORP COM 12,393 12,393 New 970,495
ALERE INC COM 10,977 -3,180 (22.46) 286,540
QUESTCOR PHARMACEUTICALS INC COM 10,884 10,884 New 117,080
SAGENT PHARMACEUTICALS INC COM 10,685 2,257 26.78 404,731
CATAMARAN CORP COM 10,210 3,757 58.22 231,000
BIODELIVERY SCIENCES INTL INC COM 9,579 1,422 17.43 683,260
VERASTEM INC COM 7,939 -864 (9.82) 918,827


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