TEKLA CAPITAL MANAGEMENT LLC Information

2 LIBERTY SQUARE, BOSTON, Massachusetts, 02109, (617) 772-8500

Report Date: 09/30/2014

Position Statistics

Total Positions 90
New Positions 29
Increased Positions 66
Decreased Positions 2
Positions with Activity 68
Sold Out Positions 1
Total Mkt Value (in $ millions) 2,217

Institutional Holdings information is filed by major institutions on form 13-F with the Securities and Exchange Commission.

Sector Weighting

Basic Materials
Capital Goods
Conglomerates 0.19%
Consumer Cyclical
Consumer/Non-Cyclical
Energy
Financial 4.31%
Healthcare 86.69%
Services 3.5%
Technology 2.83%
Transportation
Utilities

68 Activity Positions as of 09/30/2014

Company Class Value of Shares ($1,000s) ▼ Change in Value ($1,000s) Change (%) Shares Held
GILEAD SCIENCES INC COM 251,818 99,676 65.52 2,490,531
CELGENE CORP COM 226,187 121,326 115.70 2,036,434
ALEXION PHARMACEUTICALS INC COM 87,114 22,362 34.54 451,905
INCYTE CORP COM 83,523 27,334 48.65 1,141,961
AMGEN INC COM 82,749 9,815 13.46 510,042
VERTEX PHARMACEUTICALS INC COM 80,155 18,385 29.76 701,944
REGENERON PHARMACEUTICALS COM 77,300 -2,602 (3.26) 187,166
ACTAVIS PLC SHS 75,046 9,563 14.60 277,631
BIOMARIN PHARMACEUTICAL INC COM 63,557 25,864 68.62 710,527
PFIZER INC COM 57,961 47,755 467.91 1,902,241
BIOGEN IDEC INC COM 57,044 3,909 7.36 186,783
MYLAN INC COM 56,738 20,103 54.87 1,010,105
ALLERGAN INC COM 48,407 15,186 45.71 228,227
ILLUMINA INC COM 43,394 23,746 120.86 229,341
CUBIST PHARMACEUTICALS INC COM 37,064 17,292 87.46 494,454
TEVA PHARMACEUTICAL INDS LTD ADR 36,901 19,278 109.39 652,194
JOHNSON & JOHNSON COM 34,914 34,914 New 327,212
THERMO FISHER SCIENTIFIC INC COM 34,128 26,499 347.33 266,875
AETNA INC NEW COM 33,694 12,254 57.16 389,031
ABBVIE INC COM 32,752 32,752 New 481,219