TEKLA CAPITAL MANAGEMENT LLC Information

2 LIBERTY SQUARE, BOSTON, Massachusetts, 02109, (617) 772-8500

Report Date: 03/31/2014

Position Statistics

Total Positions 63
New Positions 7
Increased Positions 20
Decreased Positions 16
Positions with Activity 36
Sold Out Positions 4
Total Mkt Value (in $ millions) 1,142

Institutional Holdings information is filed by major institutions on form 13-F with the Securities and Exchange Commission.

Sector Weighting

Basic Materials
Capital Goods
Conglomerates
Consumer Cyclical
Consumer/Non-Cyclical
Energy
Financial 5.19%
Healthcare 86.69%
Services 0.91%
Technology 3.32%
Transportation
Utilities

63 Positions as of 03/31/2014

Company Class Value of Shares ($1,000s) ▼ Change in Value ($1,000s) Change (%) Shares Held
GILEAD SCIENCES INC COM 135,936 New 1,504,712
CELGENE CORP COM 84,137 -6,773 (7.45) 944,092
REGENERON PHARMACEUTICALS COM 65,518 -15,369 (19) 211,166
BIOGEN IDEC INC COM 58,737 -6,077 (9.38) 173,983
ALEXION PHARMACEUTICALS INC COM 58,137 -6,132 (9.54) 335,899
ACTAVIS PLC SHS 55,882 New 254,436
AMGEN INC COM 54,849 4,563 9.08 449,543
VERTEX PHARMACEUTICALS INC COM 49,047 New 499,764
PUMA BIOTECHNOLOGY INC COM 43,376 New 185,820
SHIRE PLC SPONSORED ADR 39,314 New 154,153
ALLERGAN INC COM 37,303 8,580 29.87 216,337
MYLAN INC COM 34,137 8,584 33.59 652,209
INCYTE CORP COM 27,335 -1,480 (5.14) 558,080
ISHARES NASDQ BIOTEC ETF 26,473 -8,824 (25) 102,080
PERRIGO CO PLC SHS 26,403 -8,375 (24.08) 167,874
BIOMARIN PHARMACEUTICAL INC COM 26,160 10,128 63.18 421,384
AKORN INC COM 24,003 -8,112 (25.26) 699,382
AETNA INC NEW COM 20,868 New 246,841
ILLUMINA INC COM 18,758 New 103,841
TEVA PHARMACEUTICAL INDS LTD ADR 17,147 New 311,476