RA CAPITAL MANAGEMENT, LLC Information

20 PARK PLAZA, SUITE 1200, BOSTON, Massachusetts, 02116, (617) 778-2500

Report Date: 03/31/2014

Position Statistics

Total Positions 30
New Positions 7
Increased Positions 12
Decreased Positions 8
Positions with Activity 20
Sold Out Positions 1
Total Mkt Value (in $ millions) 955

Institutional Holdings information is filed by major institutions on form 13-F with the Securities and Exchange Commission.

Sector Weighting

Basic Materials
Capital Goods
Conglomerates 1.17%
Consumer Cyclical
Consumer/Non-Cyclical
Energy
Financial
Healthcare 72.38%
Services 5.64%
Technology
Transportation
Utilities

30 Positions as of 03/31/2014

Company Class Value of Shares ($1,000s) ▼ Change in Value ($1,000s) Change (%) Shares Held
ACHILLION PHARMACEUTICALS INC COM 161,225 New 23,366,007
OPHTHOTECH CORP COM 72,851 5,760 8.59 1,737,856
SANGAMO BIOSCIENCES INC COM 70,602 -71 (0.1) 5,222,053
DYAX CORP COM 63,954 50,024 359.13 7,436,470
ENANTA PHARMACEUTICALS INC COM 61,227 61,227 New 1,541,078
THERAPEUTICSMD INC COM 53,816 -9,964 (15.62) 9,838,449
BIOCRYST PHARMACEUTICALS COM 50,691 New 4,347,456
DICERNA PHARMACEUTICALS INC COM 47,163 47,163 New 2,428,571
NOVAVAX INC COM 43,132 -3,792 (8.08) 9,938,250
ARROWHEAD RESH CORP COM NEW 33,538 10,177 43.56 2,941,916
PROTHENA CORP PLC SHS 32,949 -1,828 (5.26) 1,554,918
SUNESIS PHARMACEUTICALS INC COM NEW 29,995 New 4,869,261
XENCOR INC COM 28,040 New 2,725,000
DYNAVAX TECHNOLOGIES CORP COM 27,362 New 17,883,954
PTC THERAPEUTICS INC COM 24,593 5,745 30.48 981,761
REPROS THERAPEUTICS INC COM NEW 22,723 22,723 New 1,439,048
TESARO INC COM 22,225 New 700,000
NEUROCRINE BIOSCIENCES INC COM 16,636 16,636 New 1,169,084
BLUEBIRD BIO INC COM 16,053 New 467,418
DERMA SCIENCES INC COM PAR $.01 15,265 -7,477 (32.88) 1,339,039


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