ORBIMED ADVISORS LLC Information

601 LEXINGTON AVENUE, NEW YORK, New York, 10022, (212) 739-6400

Report Date: 03/31/2013

Position Statistics:

Total Positions 109
New Positions 12
Increased Positions 54
Decreased Positions 31
Positions with Activity 85
Sold Out Positions 5
Total Mkt Value
(in $ millions)
4,380

Sector Weighting

Basic Materials
Capital Goods
Conglomerates 0.12%
Consumer Cyclical
Consumer/Non-Cyclical
Energy
Financial 5.42%
Healthcare 87.61%
Services 2.76%
Technology 4.08%
Transportation
Utilities

Institutional Holdings information is filed by major institutions on form 13-F with the Securities and Exchange Commission.

31 DECREASED Positions as of 03/31/2013

Company Class Value of Shares ($1,000s) Change in Value ($1,000s) Change (%) Shares Held
BIOGEN IDEC INC COM 165,433 -18,762 (10.19) 709,800
ILLUMINA INC COM 114,080 -3,817 (3.24) 1,613,800
ONYX PHARMACEUTICALS INC COM 112,380 -19,657 (14.89) 1,208,000
MERCK & CO INC NEW COM 103,603 -25,831 (19.96) 2,218,000
ABBVIE INC COM 94,455 -32,592 (25.65) 2,020,000
ABBOTT LABS COM 66,085 -36,400 (35.52) 1,752,000
WARNER CHILCOTT PLC IRELAND SHS A 61,722 -15,287 (19.85) 3,048,000
LIFE TECHNOLOGIES CORP COM 59,058 -82,066 (58.15) 797,000
MEDIVATION INC COM 56,792 -12,290 (17.79) 1,170,000
ZIMMER HLDGS INC COM 41,072 -240 (0.58) 514,300
EXACT SCIENCES CORP COM 39,545 -6,785 (14.65) 3,737,700
BAXTER INTL INC COM 37,596 -289 (0.76) 520,000
ALLERGAN INC COM 30,492 -7,525 (19.79) 312,000
PACIRA PHARMACEUTICALS INC COM 28,208 -18,902 (40.12) 970,000
AETNA INC NEW COM 25,181 -179 (0.7) 423,000
AFFYMETRIX INC COM 24,951 -119 (0.47) 6,798,700
ORASURE TECHNOLOGIES INC COM 23,542 -109 (0.46) 5,412,000
PUMA BIOTECHNOLOGY INC COM 23,158 -8,037 (25.77) 631,000
NATUS MEDICAL INC DEL COM 22,030 -108 (0.49) 1,568,000
FLUIDIGM CORP DEL COM 22,025 -1,443 (6.15) 1,285,000

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