BB BIOTECH AG Information

VORDERGASSE 3, SCHAFFHAUSEN, , CH-8200, (411) 724-5959

Report Date: 12/31/2014

Position Statistics

Total Positions 29
New Positions 3
Increased Positions 13
Decreased Positions 11
Positions with Activity 24
Sold Out Positions 1
Total Mkt Value (in $ millions) 3,778

Institutional Holdings information is filed by major institutions on form 13-F with the Securities and Exchange Commission.

Sector Weighting

Basic Materials
Capital Goods
Conglomerates 2.93%
Consumer Cyclical
Consumer/Non-Cyclical
Energy
Financial
Healthcare 89.5%
Services
Technology
Transportation
Utilities

29 Positions as of 12/31/2014

Company Class Value of Shares ($1,000s) ▼ Change in Value ($1,000s) Change (%) Shares Held
CELGENE CORP COM 440,924 -20,774 (4.5) 3,714,298
INCYTE CORP COM 434,927 -26,835 (5.81) 4,051,867
ISIS PHARMACEUTICALS INC COM 396,662 -43,804 (9.95) 5,976,526
GILEAD SCIENCES INC COM 305,444 15,554 5.37 2,945,596
AGIOS PHARMACEUTICALS INC COM 199,621 -2,740 (1.35) 1,864,921
PHARMACYCLICS INC COM 187,706 New 731,542
MEDIVATION INC COM 181,410 -5,895 (3.15) 1,384,706
VERTEX PHARMACEUTICALS INC COM 180,412 New 1,354,445
NEUROCRINE BIOSCIENCES INC COM 133,864 -1,301 (0.96) 3,086,552
SYNAGEVA BIOPHARMA CORP COM 122,668 4,015 3.38 1,130,476
ALEXION PHARMACEUTICALS INC COM 121,091 -9,904 (7.56) 672,428
PUMA BIOTECHNOLOGY INC COM 115,934 9,995 9.43 521,991
HALOZYME THERAPEUTICS INC COM 115,078 6,660 6.14 6,825,532
RADIUS HEALTH INC COM NEW 112,865 291 .26 2,752,140
RECEPTOS INC COM 110,626 2,448 2.26 651,181
REGENERON PHARMACEUTICALS COM 95,058 -16,803 (15.02) 198,000
ALNYLAM PHARMACEUTICALS INC COM 89,411 -3,570 (3.84) 751,288
PTC THERAPEUTICS INC COM 86,543 86,543 New 1,227,912
NOVAVAX INC COM 67,782 3,432 5.33 7,900,000
CLOVIS ONCOLOGY INC COM 56,892 5,522 10.75 618,188


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