BAKER BROS. ADVISORS LP Information

667 MADISON AVE, NEW YORK, New York, 10065, (212) 339-5600

Report Date: 06/30/2014

Position Statistics

Total Positions 101
New Positions 6
Increased Positions 27
Decreased Positions 15
Positions with Activity 42
Sold Out Positions 6
Total Mkt Value (in $ millions) 5,816

Institutional Holdings information is filed by major institutions on form 13-F with the Securities and Exchange Commission.

Sector Weighting

Basic Materials
Capital Goods
Conglomerates 1.07%
Consumer Cyclical
Consumer/Non-Cyclical
Energy
Financial
Healthcare 96.37%
Services
Technology
Transportation
Utilities

101 Positions as of 06/30/2014

Company Class Value of Shares ($1,000s) Change in Value ($1,000s) Change (%) Shares Held ▲
ASSEMBLY BIOSCIENCES INC COM -747 Sold Out 0
AUXILIUM PHARMACEUTICALS INC COM -1,793 Sold Out 0
INTERCEPT PHARMACEUTICALS INC COM -57,543 Sold Out 0
PORTOLA PHARMACEUTICALS INC COM -4,729 Sold Out 0
PROTHENA CORP PLC SHS -4,594 Sold Out 0
RETROPHIN INC COM -1,830 Sold Out 0
ALNYLAM PHARMACEUTICALS INC COM 1,000 New 11,600
CYCLACEL PHARMACEUTICALS INC PFD CONV EX 6% 97 New 13,253
ASTERIAS BIOTHERAPEUTICS INC COM SER A 85 New 16,774
FIVE PRIME THERAPEUTICS INC COM 238 New 19,823
BIOTIME INC WT EXP 100118 18 New 20,525
RECEPTOS INC COM 1,537 New 23,900
ACCELERON PHARMA INC COM 834 New 28,765
UNIQURE NV SHS 301 New 30,672
TESARO INC COM 800 New 31,218
OPHTHOTECH CORP COM 1,467 New 36,776
CHEMOCENTRYX INC COM 264 New 50,000
LIGAND PHARMACEUTICALS INC COM NEW 3,675 New 73,400
ENANTA PHARMACEUTICALS INC COM 3,284 -244 (6.92) 75,357
FOUNDATION MEDICINE INC COM 1,792 1,792 New 78,162


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