BAKER BROS. ADVISORS LP Information

667 MADISON AVE, NEW YORK, New York, 10065, (212) 339-5600

Report Date: 06/30/2015

Position Statistics

Total Positions 125
New Positions 8
Increased Positions 32
Decreased Positions 28
Positions with Activity 60
Sold Out Positions 9
Total Mkt Value (in $ millions) 8,816

Institutional Holdings information is filed by major institutions on form 13-F with the Securities and Exchange Commission.

Sector Weighting

Basic Materials
Capital Goods
Conglomerates 1.26%
Consumer Cyclical
Consumer/Non-Cyclical
Energy
Financial
Healthcare 91.93%
Services
Technology
Transportation
Utilities

125 Positions as of 06/30/2015

Company Class ▲ Value of Shares ($1,000s) Change in Value ($1,000s) Change (%) Shares Held
ABBVIE INC COM 907,545 -42,148 (4.44) 14,373,538
ACADIA PHARMACEUTICALS COM 745,115 New 20,481,442
ACCELERON PHARMA INC COM 813 New 28,765
ACHAOGEN INC COM 674 New 100,000
ACHILLION PHARMACEUTICALS INC COM 11,184 9,612 611.24 1,523,739
ACORDA THERAPEUTICS INC COM 23,616 New 738,916
AEGERION PHARMACEUTICALS INC COM -253 Sold Out 0
AERIE PHARMACEUTICALS INC COM 4,778 New 299,356
AFFIMED N V COM 4,016 New 400,000
AGIOS PHARMACEUTICALS INC COM 8,745 -4,368 (33.31) 100,000
ALDER BIOPHARMACEUTICALS INC COM 34,366 467 1.38 891,688
ALDEYRA THERAPEUTICS INC COM 985 New 142,000
ALEXION PHARMACEUTICALS INC COM 1,135,403 -196,296 (14.74) 6,542,599
ALNYLAM PHARMACEUTICALS INC COM 1,160 New 11,340
ANACOR PHARMACEUTICALS INC COM 479,436 -76,594 (13.78) 3,625,498
AQUINOX PHARMACEUTICALS INC COM 21,912 178 .82 1,197,366
ARBUTUS BIOPHARMA CORP COM 1,264 New 180,582
ARRAY BIOPHARMA INC COM 31,141 -1,001 (3.12) 5,482,505
ASSEMBLY BIOSCIENCES INC COM 3,208 New 250,000
ATYR PHARMA INC COM 33,392 33,392 New 2,335,125


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