BAKER BROS. ADVISORS LP Information

667 MADISON AVE, NEW YORK, New York, 10065, (212) 339-5600

Report Date: 09/30/2014

Position Statistics

Total Positions 103
New Positions 8
Increased Positions 29
Decreased Positions 18
Positions with Activity 47
Sold Out Positions 6
Total Mkt Value (in $ millions) 6,856

Institutional Holdings information is filed by major institutions on form 13-F with the Securities and Exchange Commission.

Sector Weighting

Basic Materials
Capital Goods
Conglomerates 0.97%
Consumer Cyclical
Consumer/Non-Cyclical
Energy
Financial
Healthcare 96.09%
Services
Technology
Transportation
Utilities

103 Positions as of 09/30/2014

Company Class Value of Shares ($1,000s) ▼ Change in Value ($1,000s) Change (%) Shares Held
VERSARTIS INC COM 27,725 4 .02 1,246,089
HALOZYME THERAPEUTICS INC COM 25,929 New 2,776,143
HERON THERAPEUTICS INC COM 25,426 New 2,607,784
REPROS THERAPEUTICS INC COM NEW 24,674 New 2,778,654
GILEAD SCIENCES INC COM 23,380 New 256,108
MALLINCKRODT PUB LTD CO SHS 19,750 -24,132 (54.99) 201,856
CATALYST PHARM PARTNERS INC COM 19,475 13,028 202.08 6,715,462
AGIOS PHARMACEUTICALS INC COM 18,632 -3,290 (15.01) 169,893
OMEROS CORP COM 17,866 1,214 7.29 808,775
INSMED INC COM PAR $.01 16,939 12,290 264.36 1,107,850
DAIICHI SANKYO CO LTD SPON ADR LEV 1 15,443 4,878 46.18 1,093,332
BLUEBIRD BIO INC COM 13,314 -4,284 (24.34) 150,000
SANGAMO BIOSCIENCES INC COM 12,281 4,858 65.44 864,856
NEUROCRINE BIOSCIENCES INC COM 11,829 New 554,590
KYTHERA BIOPHARMACEUTICALS INC COM 10,617 New 311,255
MACROGENICS INC COM 10,292 New 311,891
XENCOR INC COM 9,128 New 542,363
AERIE PHARMACEUTICALS INC COM 8,828 New 299,356
PROQR THRAPEUTICS N V SHS EURO 7,872 7,872 New 400,000
AQUINOX PHARMACEUTICALS INC COM 7,841 New 1,211,851


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