BAKER BROS. ADVISORS LP Information

667 MADISON AVE, NEW YORK, New York, 10065, (212) 339-5600

Report Date: 06/30/2014

Position Statistics

Total Positions 100
New Positions 6
Increased Positions 27
Decreased Positions 15
Positions with Activity 42
Sold Out Positions 6
Total Mkt Value (in $ millions) 5,795

Institutional Holdings information is filed by major institutions on form 13-F with the Securities and Exchange Commission.

Sector Weighting

Basic Materials
Capital Goods
Conglomerates 1.1%
Consumer Cyclical
Consumer/Non-Cyclical
Energy
Financial
Healthcare 96.32%
Services
Technology
Transportation
Utilities

100 Positions as of 06/30/2014

Company Class Value of Shares ($1,000s) ▼ Change in Value ($1,000s) Change (%) Shares Held
GILEAD SCIENCES INC COM 27,263 -31,935 (53.95) 256,108
HALOZYME THERAPEUTICS INC COM 25,263 -26,590 (51.28) 2,776,143
VERSARTIS INC COM 23,659 23,659 New 1,245,889
PROGENICS PHARMACEUTICALS INC COM 23,094 New 4,449,797
TG THERAPEUTICS INC COM 23,057 New 2,160,965
HERON THERAPEUTICS INC COM 21,723 3,665 20.30 2,607,784
XENOPORT INC COM 21,704 New 4,034,112
ARROWHEAD RESH CORP COM NEW 21,133 10,320 95.45 1,430,802
SALIX PHARMACEUTICALS INC COM 20,893 20,327 3,592.93 133,721
AEGERION PHARMACEUTICALS INC COM 13,817 -3,338 (19.46) 413,922
AGIOS PHARMACEUTICALS INC COM 12,263 New 199,893
AMBIT BIOSCIENCES CORP COM 11,518 New 747,954
TEKMIRA PHARMACEUTICALS CORP COM NEW 10,235 New 484,156
KYTHERA BIOPHARMACEUTICALS INC COM 10,197 New 311,255
OMEROS CORP COM 9,588 New 753,804
NEUROCRINE BIOSCIENCES INC COM 8,690 1,672 23.83 554,590
INFINITY PHARMACEUTICALS INC COM 8,375 New 624,050
AQUINOX PHARMACEUTICALS INC COM 8,071 New 1,211,851
CATALYST PHARM PARTNERS INC COM 7,381 5,489 290.11 2,223,053
BIODELIVERY SCIENCES INTL INC COM 7,195 New 421,005


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