BAKER BROS. ADVISORS LP Information

667 MADISON AVE, NEW YORK, New York, 10065, (212) 339-5600

Report Date: 09/30/2015

Position Statistics

Total Positions 126
New Positions 12
Increased Positions 39
Decreased Positions 12
Positions with Activity 51
Sold Out Positions 4
Total Mkt Value (in $ millions) 8,035

Institutional Holdings information is filed by major institutions on form 13-F with the Securities and Exchange Commission.

Sector Weighting

Basic Materials
Capital Goods
Conglomerates 0.76%
Consumer Cyclical
Consumer/Non-Cyclical
Energy
Financial
Healthcare 92.38%
Services
Technology
Transportation
Utilities

12 New Positions as of 09/30/2015

Company Class Value of Shares ($1,000s) ▼ Change in Value ($1,000s) Change (%) Shares Held
MEDIVATION INC COM 19,225 19,225 New 659,752
AKARI THERAPEUTICS PLC SPONSORED ADR 4,927 4,927 New 395,882
ENDOCYTE INC COM 4,097 4,097 New 1,356,552
AIMMUNE THERAPEUTICS INC COM 3,900 3,900 New 250,000
GLOBAL BLOOD THERAPEUTICS INC COM 3,716 3,716 New 200,000
TREVENA INC COM 3,389 3,389 New 450,000
NABRIVA THERAPEUTICS AG SPONSORED ADR 2,919 2,919 New 350,000
NATERA INC COM 1,795 1,795 New 250,000
DYNAVAX TECHNOLOGIES CORP COM NEW 1,579 1,579 New 75,000
PRONAI THERAPEUTICS INC COM 1,442 1,442 New 200,000
TRILLIUM THERAPEUTICS INC COM NEW 498 498 New 63,014
SYNERGY PHARMACEUTICALS DEL COM NEW 240 240 New 67,100