BAKER BROS. ADVISORS LP Information

667 MADISON AVE, NEW YORK, New York, 10065, (212) 339-5600

Report Date: 09/30/2014

Position Statistics

Total Positions 102
New Positions 8
Increased Positions 28
Decreased Positions 18
Positions with Activity 46
Sold Out Positions 6
Total Mkt Value (in $ millions) 7,375

Institutional Holdings information is filed by major institutions on form 13-F with the Securities and Exchange Commission.

Sector Weighting

Basic Materials
Capital Goods
Conglomerates 0.97%
Consumer Cyclical
Consumer/Non-Cyclical
Energy
Financial
Healthcare 96.16%
Services
Technology
Transportation
Utilities

8 New Positions as of 09/30/2014

Company Class Value of Shares ($1,000s) ▼ Change in Value ($1,000s) Change (%) Shares Held
PROQR THRAPEUTICS N V SHS EURO 8,404 8,404 New 400,000
FOAMIX PHARMACEUTICALS LTD SHS 8,275 8,275 New 1,021,600
CELLADON CORP COM 6,386 6,386 New 375,000
SAGE THERAPEUTICS INC COM 2,869 2,869 New 75,000
AURINIA PHARMACEUTICALS INC COM 2,576 2,576 New 727,669
MARINUS PHARMACEUTICALS INC COM 2,247 2,247 New 204,476
AFFIMED N V COM 2,072 2,072 New 400,000
LOXO ONCOLOGY INC COM 1,049 1,049 New 100,000