BAKER BROS. ADVISORS LP Information

667 MADISON AVE, NEW YORK, New York, 10065, (212) 339-5600

Report Date: 09/30/2014

Position Statistics

Total Positions 102
New Positions 8
Increased Positions 28
Decreased Positions 18
Positions with Activity 46
Sold Out Positions 6
Total Mkt Value (in $ millions) 7,527

Institutional Holdings information is filed by major institutions on form 13-F with the Securities and Exchange Commission.

Sector Weighting

Basic Materials
Capital Goods
Conglomerates 1.04%
Consumer Cyclical
Consumer/Non-Cyclical
Energy
Financial
Healthcare 96.1%
Services
Technology
Transportation
Utilities

102 Positions as of 09/30/2014

Company Class Value of Shares ($1,000s) ▲ Change in Value ($1,000s) Change (%) Shares Held
AEGERION PHARMACEUTICALS INC COM -9,653 Sold Out 0
ASTERIAS BIOTHERAPEUTICS INC COM SER A -66 Sold Out 0
BIOTIME INC WT EXP 100118 -26 Sold Out 0
CLOVIS ONCOLOGY INC COM -52,416 Sold Out 0
GALECTIN THERAPEUTICS INC COM NEW -1,035 Sold Out 0
REGADO BIOSCIENCES INC COM -452 Sold Out 0
CYCLACEL PHARMACEUTICALS INC PFD CONV EX 6% 80 New 13,253
CHEMOCENTRYX INC COM 441 New 50,000
FIVE PRIME THERAPEUTICS INC COM 519 New 19,823
UNIQURE NV SHS 646 New 30,672
RIGEL PHARMACEUTICALS INC COM NEW 1,036 New 481,972
ALNYLAM PHARMACEUTICALS INC COM 1,084 New 11,600
ACCELERON PHARMA INC COM 1,131 New 28,765
SALIX PHARMACEUTICALS INC COM 1,165 -16,906 (93.55) 8,621
LOXO ONCOLOGY INC COM 1,179 1,179 New 100,000
ACHAOGEN INC COM 1,205 New 100,000
SYNTA PHARMACEUTICALS CORP COM 1,235 New 500,000
TESARO INC COM 1,280 New 31,218
MAST THERAPEUTICS INC COM 1,293 New 3,000,000
GERON CORP COM 1,300 New 402,629