BAKER BROS. ADVISORS LP Information

667 MADISON AVE, NEW YORK, New York, 10065, (212) 339-5600

Report Date: 06/30/2014

Position Statistics

Total Positions 101
New Positions 6
Increased Positions 28
Decreased Positions 15
Positions with Activity 43
Sold Out Positions 6
Total Mkt Value (in $ millions) 6,302

Institutional Holdings information is filed by major institutions on form 13-F with the Securities and Exchange Commission.

Sector Weighting

Basic Materials
Capital Goods
Conglomerates 1.05%
Consumer Cyclical
Consumer/Non-Cyclical
Energy
Financial
Healthcare 96.59%
Services
Technology
Transportation
Utilities

101 Positions as of 06/30/2014

Company Class Value of Shares ($1,000s) ▲ Change in Value ($1,000s) Change (%) Shares Held
ASSEMBLY BIOSCIENCES INC COM -688 Sold Out 0
AUXILIUM PHARMACEUTICALS INC COM -1,823 Sold Out 0
INTERCEPT PHARMACEUTICALS INC COM -66,158 Sold Out 0
PORTOLA PHARMACEUTICALS INC COM -4,804 Sold Out 0
PROTHENA CORP PLC SHS -5,411 Sold Out 0
RETROPHIN INC COM -2,226 Sold Out 0
CYCLACEL PHARMACEUTICALS INC PFD CONV EX 6% 101 New 13,253
ASTERIAS BIOTHERAPEUTICS INC COM SER A 109 New 16,774
FIVE PRIME THERAPEUTICS INC COM 227 New 19,823
CHEMOCENTRYX INC COM 244 New 50,000
UNIQURE NV SHS 300 New 30,672
REGADO BIOSCIENCES INC COM 408 New 400,000
ACCELERON PHARMA INC COM 696 New 28,765
ZIOPHARM ONCOLOGY INC COM 714 New 244,619
ACHAOGEN INC COM 885 New 100,000
TESARO INC COM 893 New 31,218
ALNYLAM PHARMACEUTICALS INC COM 902 New 11,600
GERON CORP COM 906 New 402,629
RIGEL PHARMACEUTICALS INC COM NEW 1,051 New 481,972
OPHTHOTECH CORP COM 1,436 New 36,776