BAKER BROS. ADVISORS LP Information

667 MADISON AVE, NEW YORK, New York, 10065, (212) 339-5600

Report Date: 06/30/2014

Position Statistics

Total Positions 101
New Positions 6
Increased Positions 28
Decreased Positions 15
Positions with Activity 43
Sold Out Positions 6
Total Mkt Value (in $ millions) 6,106

Institutional Holdings information is filed by major institutions on form 13-F with the Securities and Exchange Commission.

Sector Weighting

Basic Materials
Capital Goods
Conglomerates 1.07%
Consumer Cyclical
Consumer/Non-Cyclical
Energy
Financial
Healthcare 96.64%
Services
Technology
Transportation
Utilities

101 Positions as of 06/30/2014

Company Class Value of Shares ($1,000s) ▲ Change in Value ($1,000s) Change (%) Shares Held
ASSEMBLY BIOSCIENCES INC COM -574 Sold Out 0
AUXILIUM PHARMACEUTICALS INC COM -1,081 Sold Out 0
INTERCEPT PHARMACEUTICALS INC COM -73,608 Sold Out 0
PORTOLA PHARMACEUTICALS INC COM -4,567 Sold Out 0
PROTHENA CORP PLC SHS -4,946 Sold Out 0
RETROPHIN INC COM -2,423 Sold Out 0
ASTERIAS BIOTHERAPEUTICS INC COM SER A 40 New 16,774
CYCLACEL PHARMACEUTICALS INC PFD CONV EX 6% 98 New 13,253
FIVE PRIME THERAPEUTICS INC COM 221 New 19,823
CHEMOCENTRYX INC COM 248 New 50,000
UNIQURE NV SHS 353 New 30,672
ALNYLAM PHARMACEUTICALS INC COM 758 New 11,600
ZIOPHARM ONCOLOGY INC COM 783 New 244,619
ACCELERON PHARMA INC COM 791 New 28,765
ACHAOGEN INC COM 904 New 100,000
TESARO INC COM 905 New 31,218
GERON CORP COM 934 New 402,629
RECEPTOS INC COM 1,119 New 23,900
REGADO BIOSCIENCES INC COM 1,136 New 400,000
RIGEL PHARMACEUTICALS INC COM NEW 1,248 New 481,972