BAKER BROS. ADVISORS LP Information

667 MADISON AVE, NEW YORK, New York, 10065, (212) 339-5600

Report Date: 09/30/2014

Position Statistics

Total Positions 103
New Positions 8
Increased Positions 29
Decreased Positions 18
Positions with Activity 47
Sold Out Positions 6
Total Mkt Value (in $ millions) 7,200

Institutional Holdings information is filed by major institutions on form 13-F with the Securities and Exchange Commission.

Sector Weighting

Basic Materials
Capital Goods
Conglomerates 0.92%
Consumer Cyclical
Consumer/Non-Cyclical
Energy
Financial
Healthcare 96.29%
Services
Technology
Transportation
Utilities

103 Positions as of 09/30/2014

Company Class Value of Shares ($1,000s) Change in Value ($1,000s) Change (%) Shares Held ▲
AEGERION PHARMACEUTICALS INC COM -9,500 Sold Out 0
ASTERIAS BIOTHERAPEUTICS INC COM SER A -62 Sold Out 0
BIOTIME INC WT EXP 100118 -19 Sold Out 0
CLOVIS ONCOLOGY INC COM -45,753 Sold Out 0
GALECTIN THERAPEUTICS INC COM NEW -1,110 Sold Out 0
REGADO BIOSCIENCES INC COM -356 Sold Out 0
SALIX PHARMACEUTICALS INC COM 1,021 -14,818 (93.55) 8,621
ALNYLAM PHARMACEUTICALS INC COM 1,153 New 11,600
CYCLACEL PHARMACEUTICALS INC PFD CONV EX 6% 82 New 13,253
FIVE PRIME THERAPEUTICS INC COM 481 New 19,823
RECEPTOS INC COM 3,057 New 23,900
ACCELERON PHARMA INC COM 1,164 New 28,765
UNIQURE NV SHS 478 New 30,672
TESARO INC COM 1,163 New 31,218
OPHTHOTECH CORP COM 1,746 New 36,776
CHEMOCENTRYX INC COM 336 New 50,000
LIGAND PHARMACEUTICALS INC COM NEW 3,826 New 73,400
SAGE THERAPEUTICS INC COM 3,024 3,024 New 75,000
ENANTA PHARMACEUTICALS INC COM 3,382 New 75,357
FOUNDATION MEDICINE INC COM 1,734 New 78,162


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