BAKER BROS. ADVISORS LP Information

667 MADISON AVE, NEW YORK, New York, 10065, (212) 339-5600

Report Date: 03/31/2014

Position Statistics

Total Positions 100
New Positions 17
Increased Positions 36
Decreased Positions 51
Positions with Activity 87
Sold Out Positions 6
Total Mkt Value (in $ millions) 5,485

Institutional Holdings information is filed by major institutions on form 13-F with the Securities and Exchange Commission.

Sector Weighting

Basic Materials
Capital Goods
Conglomerates 1.07%
Consumer Cyclical
Consumer/Non-Cyclical
Energy
Financial
Healthcare 97.6%
Services
Technology
Transportation
Utilities

100 Positions as of 03/31/2014

Company Class Value of Shares ($1,000s) Change in Value ($1,000s) Change (%) Shares Held ▲
CONTRAVIR PHARMACEUTICALS INC COM -347 Sold Out 0
FOUNDATION MEDICINE INC COM -493 Sold Out 0
GW PHARMACEUTICALS PLC ADS -8,444 Sold Out 0
MEDIVATION INC COM -29,879 Sold Out 0
PUMA BIOTECHNOLOGY INC COM -1,636 Sold Out 0
UNITED THERAPEUTICS CORP DEL COM -1,865 Sold Out 0
SALIX PHARMACEUTICALS INC COM 477 New 3,621
ALNYLAM PHARMACEUTICALS INC COM 665 665 New 11,600
CYCLACEL PHARMACEUTICALS INC PFD CONV EX 6% 103 -60 (36.83) 13,253
FIVE PRIME THERAPEUTICS INC COM 289 New 19,823
RECEPTOS INC COM 905 -2,881 (76.1) 23,900
ACCELERON PHARMA INC COM 872 -37 (4.12) 28,765
UNIQURE NV SHS 406 406 New 30,672
TESARO INC COM 956 New 31,218
OPHTHOTECH CORP COM 1,521 -2,740 (64.31) 36,776
CHEMOCENTRYX INC COM 285 New 50,000
AUXILIUM PHARMACEUTICALS INC COM 1,169 1,169 New 58,544
KARYOPHARM THERAPEUTICS INC COM 2,162 -82 (3.64) 59,095
LIGAND PHARMACEUTICALS INC COM NEW 4,676 New 73,400
ENANTA PHARMACEUTICALS INC COM 3,285 -1,142 (25.79) 80,957


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