BAKER BROS. ADVISORS LP Information

667 MADISON AVE, NEW YORK, New York, 10065, (212) 339-5600

Report Date: 03/31/2015

Position Statistics

Total Positions 125
New Positions 17
Increased Positions 40
Decreased Positions 59
Positions with Activity 99
Sold Out Positions 8
Total Mkt Value (in $ millions) 10,857

Institutional Holdings information is filed by major institutions on form 13-F with the Securities and Exchange Commission.

Sector Weighting

Basic Materials
Capital Goods
Conglomerates 1.16%
Consumer Cyclical
Consumer/Non-Cyclical
Energy
Financial
Healthcare 93.09%
Services
Technology
Transportation
Utilities

125 Positions as of 03/31/2015

Company Class Value of Shares ($1,000s) ▼ Change in Value ($1,000s) Change (%) Shares Held
VERSARTIS INC COM 43,530 10,170 30.49 2,977,396
XENOPORT INC COM 41,134 -2,496 (5.72) 6,508,622
ARRAY BIOPHARMA INC COM 38,989 29,110 294.67 5,658,755
INSMED INC COM PAR $.01 38,051 11,430 42.93 1,583,490
TG THERAPEUTICS INC COM 33,707 New 2,050,313
CATALYST PHARMACEUTICALS INC COM 33,439 3,757 12.66 7,565,462
PROGENICS PHARMACEUTICALS INC COM 30,325 -690 (2.23) 4,350,808
GILEAD SCIENCES INC COM 28,759 -703 (2.39) 249,995
KYTHERA BIOPHARMACEUTICALS INC COM 26,545 5,096 23.76 354,265
NEUROCRINE BIOSCIENCES INC COM 25,653 -584 (2.23) 542,236
IDERA PHARMACEUTICALS INC COM NEW 25,424 19,481 327.81 6,965,432
DERMA SCIENCES INC COM PAR $.01 24,239 -556 (2.24) 3,457,841
BLUEBIRD BIO INC COM 23,923 -558 (2.28) 146,581
ACORDA THERAPEUTICS INC COM 23,704 -533 (2.2) 738,916
VANDA PHARMACEUTICALS INC COM 22,105 -34,378 (60.86) 1,750,230
NOVAVAX INC COM 21,169 7,859 59.04 1,945,687
XENCOR INC COM 19,360 6,232 47.47 872,072
FOAMIX PHARMACEUTICALS LTD SHS 19,131 8,404 78.34 1,821,967
CLOVIS ONCOLOGY INC COM 16,806 New 202,630
AGIOS PHARMACEUTICALS INC COM 16,561 -1,484 (8.23) 149,954


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