BAKER BROS. ADVISORS LP Information

667 MADISON AVE, NEW YORK, New York, 10065, (212) 339-5600

Report Date: 06/30/2014

Position Statistics

Total Positions 101
New Positions 6
Increased Positions 28
Decreased Positions 15
Positions with Activity 43
Sold Out Positions 6
Total Mkt Value (in $ millions) 6,201

Institutional Holdings information is filed by major institutions on form 13-F with the Securities and Exchange Commission.

Sector Weighting

Basic Materials
Capital Goods
Conglomerates 1.07%
Consumer Cyclical
Consumer/Non-Cyclical
Energy
Financial
Healthcare 96.62%
Services
Technology
Transportation
Utilities

28 INCREASED Positions as of 06/30/2014

Company Class Value of Shares ($1,000s) ▼ Change in Value ($1,000s) Change (%) Shares Held
PHARMACYCLICS INC COM 1,169,114 104,052 9.77 9,591,546
SEATTLE GENETICS INC COM 967,429 74,597 8.36 22,472,229
SYNAGEVA BIOPHARMA CORP COM 799,852 919 .12 10,660,432
INCYTE CORP COM 767,218 517 .07 14,845,559
GENOMIC HEALTH INC COM 385,478 21 .01 13,654,902
INTERMUNE INC COM 251,776 21,219 9.20 4,722,869
BIOCRYST PHARMACEUTICALS COM 151,383 69,831 85.63 10,890,872
BIOMARIN PHARMACEUTICAL INC COM 129,741 1,700 1.33 1,908,230
AVANIR PHARMACEUTICALS INC CL A NEW 108,938 74,950 220.52 18,558,487
XOMA CORP DEL COM 100,798 37 .04 23,065,972
ANACOR PHARMACEUTICALS INC COM 66,715 3,137 4.93 3,248,043
DYAX CORP COM 55,676 30,865 124.40 5,681,237
CERUS CORP COM 39,142 6,843 21.19 10,246,591
CLOVIS ONCOLOGY INC COM 34,910 11,585 49.67 793,221
VERSARTIS INC COM 25,354 25,354 New 1,245,889
HERON THERAPEUTICS INC COM 24,070 4,061 20.30 2,607,784
ARROWHEAD RESH CORP COM NEW 20,861 10,188 95.45 1,430,802
SALIX PHARMACEUTICALS INC COM 18,610 18,106 3,592.93 133,721
NEUROCRINE BIOSCIENCES INC COM 8,746 1,683 23.83 554,590
OSIRIS THERAPEUTICS INC NEW COM 7,557 2,206 41.24 510,606


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