ARTAL GROUP S.A. Information

10-12 AVENUE PASTEUR, LUXEMBOURG, , L-2310, (352) 224-2591

Report Date: 12/31/2015

Position Statistics

Total Positions 47
New Positions 8
Increased Positions 17
Decreased Positions 12
Positions with Activity 29
Sold Out Positions 2
Total Mkt Value (in $ millions) 4,534

Institutional Holdings information is filed by major institutions on form 13-F with the Securities and Exchange Commission.

Sector Weighting

Basic Materials
Capital Goods
Conglomerates 0.01%
Consumer Cyclical 0.45%
Consumer/Non-Cyclical
Energy
Financial 1.73%
Healthcare 21.53%
Services 9.57%
Technology 0.46%
Transportation 0.09%
Utilities

29 Activity Positions as of 12/31/2015

Company Class Value of Shares ($1,000s) Change in Value ($1,000s) Change (%) ▲ Shares Held
HILTON WORLDWIDE HLDGS INC COM -2,224 Sold Out 0
HOULIHAN LOKEY INC CL A -1,874 Sold Out 0
BIOMARIN PHARMACEUTICAL INC COM 23,403 -14,042 (37.5) 275,000
LINKEDIN CORP COM CL A 12,301 -3,075 (20) 100,000
JUNO THERAPEUTICS INC COM 7,988 -1,892 (19.15) 190,000
IONIS PHARMACEUTICALS INC COM 14,347 -2,050 (12.5) 350,000
SERES THERAPEUTICS INC COM 5,163 -738 (12.5) 175,000
GENERAL MTRS CO COM 12,976 -1,622 (11.11) 400,000
NEKTAR THERAPEUTICS COM 25,824 -3,228 (11.11) 1,600,000
KITE PHARMA INC COM 16,314 -1,864 (10.26) 350,000
LENDINGCLUB CORP COM 8,697 -809 (8.51) 1,075,000
CELGENE CORP COM 10,803 10,803 New 100,000
DELPHI AUTOMOTIVE PLC SHS 7,499 7,499 New 100,000
DELTA AIR LINES INC DEL COM NEW 4,286 4,286 New 100,000
DIMENSION THERAPEUTICS INC COM 1,384 1,384 New 175,000
JPMORGAN CHASE & CO COM 12,720 12,720 New 200,000
LEXICON PHARMACEUTICALS INC COM NEW 802,951 New 57,517,977
MOBILEYE N V AMSTELVEEN ORD SHS 13,853 13,853 New 350,000
QUALCOMM INC COM 8,575 8,575 New 164,500
VISA INC COM CL A 13,594 13,594 New 175,000