ADAGE CAPITAL PARTNERS GP, L.L.C. Information

200 CLARENDON STREET, BOSTON, Massachusetts, 02116, (617) 867-2800

Report Date: 12/31/2015

Position Statistics

Total Positions 767
New Positions 79
Increased Positions 310
Decreased Positions 411
Positions with Activity 721
Sold Out Positions 99
Total Mkt Value (in $ millions) 37,366

Institutional Holdings information is filed by major institutions on form 13-F with the Securities and Exchange Commission.

Sector Weighting

Basic Materials 8.11%
Capital Goods 4.45%
Conglomerates 1.03%
Consumer Cyclical 3.11%
Consumer/Non-Cyclical 7.4%
Energy 6.22%
Financial 12.48%
Healthcare 12.2%
Services 15.29%
Technology 15.2%
Transportation 2.38%
Utilities 4.27%

721 Activity Positions as of 12/31/2015

Company Class Value of Shares ($1,000s) ▼ Change in Value ($1,000s) Change (%) Shares Held
LIBERTY MEDIA CORP DELAWARE CL A 3,906 3,906 New 100,000
ENTELLUS MED INC COM 3,877 3,877 New 266,630
INSYS THERAPEUTICS INC NEW COM NEW 3,840 3,840 New 265,000
CONTRAFECT CORP COM 3,530 3,387 2,375.25 1,000,000
PERKINELMER INC COM 3,471 -106 (2.96) 68,843
STANLEY BLACK & DECKER INC COM 3,470 -73,082 (95.47) 31,005
INDEPENDENCE CONTRACT DRIL INC COM 3,376 1,194 54.72 848,201
DENTSPLY SIRONA INC COM 3,207 2,343 271.01 53,815
TEAM HEALTH HOLDINGS INC COM 3,137 3,137 New 75,000
CHARLES RIV LABS INTL INC COM 3,131 3,131 New 39,500
OMNICOM GROUP INC COM 3,054 3,054 New 36,803
ORBCOMM INC COM 3,041 3,041 New 306,853
VALEANT PHARMACEUTICALS INTL I COM 2,836 -3,169 (52.78) 85,000
FOSSIL GROUP INC COM 2,589 -32 (1.24) 63,937
CHESAPEAKE UTILS CORP COM 2,525 -16,526 (86.75) 42,415
GENESIS HEALTHCARE INC CL A COM 2,519 251 11.08 999,700
SIGNET JEWELERS LIMITED SHS 2,464 -13,190 (84.26) 22,700
CYPRESS SEMICONDUCTOR CORP COM 2,339 -4,289 (64.71) 259,000
HORTONWORKS INC COM 2,314 2,314 New 200,000
EPIRUS BIOPHARMACEUTICALS INC COM 2,239 725 47.89 772,007