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Pfizer & Bristol-Myers to Release Highly Anticipated Data on Bloodthinner Hopeful
8/22/2011 6:04:00 PM
(Written by Alexander Crawford. Data sourced from Finviz.)
Pfizer (PFE) and Bristol-Myers Squibb (BMY) may be introducing the biggest selling bloodthinner in a $9 billion market, according to Reuters. This depends on final Phase III data of their drug apixaban (sold as Eliquis) to be released next week at a meeting of the European Society of Cardiology.
Headline results of the Phase III study released this June showed Eliquis was more effective and safer than the decades-old warfarin in preventing strokes in patients with irregular heart rhythms.
On August 28, the companies will release detailed data of the 18,000-patient clinical trial, which could indicate that Eliquis is the “first oral anticoagulant to show a statistically significant improvement in mortality over warfarin in atrial fibrillation (AF) patients,” according to Reuters.
Analysts at Barclays believe that such data “would allow Eliquis to grab 50 percent of a likely $9 billion-a-year AF stroke prevention market by 2021.”
“Industry analysts, on average, currently expect 2015 sales of $1.6 billion for the product, which is due to be submitted for regulatory approval this year,” according to Thomson Reuters Pharma.
“Confirmation of strong efficacy and low bleeding risk could boost Bristol-Myers shares some 5 percent and lift Pfizer by 2-3 percent,” Chris Schott of JP Morgan told Reuters.
Analysts estimate that the warfarin replacement market can be a $10-20 billion market, but that low-cost warfarin will not disappear because patients controlled on the medication would mostly stay on it.
The promise of Eliquis is certainly welcomed, considering that Bristol-Myers and Pfizer together face more than $30 billion in revenue loss through 2016 due to patent expiries, according to Barclays.
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