Pharmacyclics Gains on Imbruvica Label Expansion - Analyst Blog

By
A A A

Pharmacyclics, Inc. ( PCYC ) and Johnson & Johnson ( JNJ ) received encouraging news with Imbruvica's label being expanded in the U.S. as a monotherapy for patients suffering from chronic lymphocytic leukemia (CLL) with a history of receiving at least one prior therapy. Pharmacyclics' shares were up more than 3% on the news.

The label expansion in the CLL indication has triggered a $60 million milestone payment to Pharmacyclics from Johnson & Johnson.

This is the second approval for Pharmacyclics' lead and only product, Imbruvica. The drug was earlier approved by the U.S. Food and Drug Administration (FDA) in Nov 2013 as a monotherapy for treating patients suffering from mantle cell lymphoma (MCL). The drug has been approved to treat MCL patients who have been treated at least once for the disease. We note that both the indications for Imbruvica are based on overall response rates, while improvements in survival or disease-related symptoms have not been established.

We are encouraged by Pharmacyclics' progress with Imbruvica. Imbruvica is currently under review in the EU for CLL and MCL. Meanwhile, companies like Roche ( RHHBY ) also have a presence in the CLL market.

Pharmacyclics is also developing Imbruvica for the treatment of multiple myeloma (phase II) and diffuse large B-cell lymphoma (phase II), follicular lymphoma (phase II) and Waldenstrom's macroglobulinemia (phase II).

Pharmacyclics, a biopharma company, currently carries a Zacks Rank #2 (Buy). A better-ranked stock in the same sector is Alexion Pharmaceuticals, Inc. ( ALXN ). Alexion holds a Zacks Rank #1 (Strong Buy).



ALEXION PHARMA (ALXN): Free Stock Analysis Report

JOHNSON & JOHNS (JNJ): Free Stock Analysis Report

PHARMACYCLICS (PCYC): Free Stock Analysis Report

ROCHE HLDG LTD (RHHBY): Free Stock Analysis Report

To read this article on Zacks.com click here.

Zacks Investment Research



The views and opinions expressed herein are the views and opinions of the author and do not necessarily reflect those of The NASDAQ OMX Group, Inc.



This article appears in: Investing , Business , Stocks

Referenced Stocks: ALXN , JNJ , PCYC , RHHBY

Zacks.com

Zacks.com

More from Zacks.com:

Related Videos

Your Car Is Spying on You
Your Car Is Spying on You           

Stocks

Referenced

Most Active by Volume

41,331,221
  • $28.495 ▼ 9.71%
31,173,491
  • $100.9867 ▲ 0.45%
28,659,591
  • $8.20 ▲ 2.24%
23,343,008
  • $5.7001 ▲ 24.73%
21,597,776
  • $15.435 ▼ 0.10%
19,891,002
  • $10.44 ▲ 1.85%
18,178,885
  • $12.64 ▲ 9.06%
17,250,764
  • $11.375 ▼ 2.11%
As of 8/20/2014, 01:17 PM

Find a Credit Card

Select a credit card product by:
Select an offer:
Search
Data Provided by BankRate.com