Coronado Biosciences, Inc. 's ( CNDO ) shares have moved up 5.71% since the company announced that the U.S. Patent and Trademark Office (USPTO) has granted a second key patent for its novel oncology candidate, CNDO-109.ACTELION LTD (ALIOF): Get Free ReportCORONADO BIOSCI (CNDO): Free Stock Analysis ReportEMERGENT BIOSOL (EBS): Free Stock Analysis ReportGENTIUM SPA-ADR (GENT): Free Stock Analysis ReportTo read this article on Zacks.com click here.Zacks Investment Research
The USPTO has also issued a Notice of Allowance for an additional pending composition-of-matter patent application. CNDO-109 annihilates cancer cells by activating the natural killer (NK) cells of the immune system. The first key patent covering CNDO-109, granted in Sep 2012, is related to the preparation of activated NK cells.
Coronado Biosciences acquired worldwide development and commercialization rights to CNDO-109 from the University College of London (UCL) Business in Nov 2007.
CNDO-109 is currently being evaluated in a phase I/II dose escalation study for the treatment of minimal residual disease in patients with relapsed/refractory acute myeloid leukemia (AML). In an earlier phase I investigator-sponsored study (n =8), it was observed by the investigators that more number of patients experienced longer complete remission using CNDO-109 than their previous complete remission.
In Jun 2012, the U.S. Food and Drug Administration (FDA) had granted orphan drug designation to CNDO-109 for the treatment of AML.
In preclinical studies, CNDO-109 has shown encouraging activity in other indications as well including multiple myeloma, breast cancer, prostate cancer and ovarian cancer.
Coronado Biosciences, a biopharmaceutical company, currently has a Zacks Rank #2 (Buy). Other biopharma stocks, worth considering, include Gentium ( GENT ), Emergent BioSolutions, Inc. ( EBS ) and Actelion Ltd. ( ALIOF ). All three sport a Zacks Rank #1 (Strong Buy).